Episode 994 Scott Adams - Convalescent Blood Plasma, Biden, Golf, and Scarborough
My new book LOSERTHINK, available now on Amazon https://tinyurl.com/rqmjc2a Content: President Trump, Joe Scarborough and an intern Special Guest: Ian Hilgart-Martiszus @IanFelipeSays Convalescent Blood (Plasma) Therapy cure-hub.com for antibody testing Gaffing and decomposing in your basement is gold for poll numbers Alyssa Milano's crochet mask...it was a trap! ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ If you would like to enjoy this same content plus bonus content from Scott Adams, including micro-lessons on lots of useful topics to build your talent stack, please see scottadams.locals.com for full access to that secret treasure.
Um, did you wonder where I was? I'm two minutes late. I couldn't get my Wi-Fi working. A little power outage last night screwed things up, but I'm good now. We're back, and that means it's time for a little thing you call the simultaneous sip. I call it that too.
View segment →And all it takes is a cup of mud or a glass of tankard or any kind of vessel that can hold your favorite liquid. I like coffee. And join me now for the unparalleled pleasure, the dopamine hit at the end of the day, the thing that makes everything better, including the damn pandemic. It's called the…
View segment →Now if you joined us last night I had a little technical difficulty. I was trying to bring on a special guest to talk about convalescent blood serum, and as soon as he's ready we're going to try that again this morning. So I'll wait till I see when Ian gets on. All right, let's tell him we're good n…
View segment →All right, let's see if we get Ian on the line. This will be a test of the technology. I think we got it. I think we got it. Oh, seriously? Because I know we had a Wi-Fi problem yesterday and it looks like we got a Wi-Fi problem today. Well whatever the problem is, it doesn't look like that's going…
View segment →So I've been watching the comments and I just want to call out something that I always talked about: winning attitudes and losing attitudes. And I'm watching a lot of losing attitudes in the comments, specifically people who don't quite appreciate, and I'm going to make them appreciate it now, the p…
View segment →All right so thank you. Thank you again. Thanks for being a great guest. I'm going to go on with the rest of my program and I'll catch up with you. Can I do one thing? I missed the simultaneous sip. Can I get another one live? I gotta do it. All right I will give you the first ever second simultaneo…
View segment →All right so you know as much as the topic is interesting because in my opinion it's probably the most important topic besides masks, but I also wanted you to get a feel for Ian. You know just a feel for what your fellow citizens, if you're American, and I'm sure it's happening in every country arou…
View segment →All right let's talk about some other things. I got a suggestion on the Locals platform where I've moved a lot of my non-Dilbert stuff. From Anholt, I don't know that's one name, and Nolt and Alt anyway I don't know his real name but he started referring to people who watched CNN and MSNBC as the po…
View segment →Now if you've done the math, I did this last night in Periscope, I was talking about all the things which have cut the risk down. So masks are supposed to be 75 percent effective. Distance of course is completely effective. Maybe vitamin D. Maybe summer will make a difference in the warm weather. Ma…
View segment →All right well I'm impressed with you all and I'm going to leave you on that note. Hope you learned something today and I'll talk to you tonight.
View segment →Um, did you wonder where I was? I'm two minutes late. I couldn't get my Wi-Fi working. A little power outage last night screwed things up, but I'm good now. We're back, and that means it's time for a little thing you call the simultaneous sip. I call it that too. And all it takes is a cup of mud or a glass of tankard or any kind of vessel that can hold your favorite liquid. I like coffee. And join me now for the unparalleled pleasure, the dopamine hit at the end of the day, the thing that makes everything better, including the damn pandemic. It's called the simultaneous sip, and it happens now.
Go. Mmm.
Now if you joined us last night I had a little technical difficulty. I was trying to bring on a special guest to talk about convalescent blood serum, and as soon as he's ready we're going to try that again this morning. So I'll wait till I see when Ian gets on. All right, let's tell him we're good now.
In the news, my favorite story is that President Trump apparently wanted to go golfing this weekend but he didn't want it to be the biggest story. So what do you do if you want to go golfing and you're the president and you don't want it to be the biggest story for three days? Well, on the way out the door to golf, what you do is you send a tweet that accuses Joe Scarborough of murder. You have to appreciate how much fun that is. Now of course not for the family of the victim who died many years ago, but the fact that Trump would accuse somebody of murder before he goes golfing is beautiful.
So I see Ian has joined. So let me just finish the story a little. Adam, on. Here's my take on that. Now on one hand it's completely outrageous and inappropriate that the President of the United States would accuse Joe Scarborough of murder when there's no indication that he actually murdered anybody. There was some young woman who hit her head and died in his office years ago. Now that's all we know, and she had some health problem that suggests that she just passed out. But the fact that the president would say that, now you say to yourself, well that's all wrong. That is so wrong. That is wrong on a level that's deeper than any wrongness, except we are talking about Joe Scarborough, who did lie about the president in the worst possible way for years.
I believe he accused the president of suggesting people should drink bleach. That never happened. I think he suggested the president had called neo-Nazis in Charlottesville fine people. That never happened. So is it fundamentally different to accuse somebody of being pro-Nazi versus saying you murdered your girlfriend? They're not that different, really, because once you have accepted that you can say absolutely anything in the political context, there's just no penalty. You can say absolutely anything. The president just took the rules and said, what are the rules? The rules are you can say anything, really just anything. I can just make up anything and I can just say it in public and it's a headline. All right, how about Joe Scarborough's a murderer? We'll see how that goes. Went pretty well.
All right, let's see if we get Ian on the line. This will be a test of the technology. I think we got it. I think we got it. Oh, seriously? Because I know we had a Wi-Fi problem yesterday and it looks like we got a Wi-Fi problem today. Well whatever the problem is, it doesn't look like that's going to get solved. I'll try it one more time but then I think we should maybe give up on this if it doesn't work this time. Yeah, and we'll try you one more time. Yeah, hey, let's make this work. This is the first time the technology has worked more than five seconds, so I feel good about it. That's a good sign. All right, good strong signal.
All right, Ian, first of all let me see if I can pronounce your name correctly. Ian Hillgard Martius? Pretty close, yes. You nailed it. All right. Can you tell the audience what your background is and how that relates specifically to the convalescent blood plasma testing situation? Give them a little background on you.
Okay, so my background is that I worked in bioscience for about ten years and then I ended up kind of leaving academic bioscience and taught myself to program and became a data analyst and started working for a corporation as a data analyst. And when the COVID stuff started to hit I would figure out ways to harvest public data to do public data analysis that I could publish so to help people understand the situation a little better. And then through that process I started to think about different answers that I thought we needed that maybe we weren't getting from the media. And one of the things I thought about was, well what can we do now? What can we do before there's a vaccine? Because there's going to be people who can't wait that long and the development of new therapeutics takes so long that a lot of people would end up dying while they wait. And so we got to figure something out in the middle.
So tell us what you did, because I was sort of following along early on and you put together your own tests, right?
Well it wasn't necessarily my own test. I bought a commercially available test kit. I just happened to become aware of its existence pretty early. I suppose the way that I became aware of it is that I just got like a spam email because when you buy something from a vendor they put you on a mailing list and then they always blast out these kind of spam advertisements. And so I got one of those that said, oh hey we have these COVID-19 antibody tests. And so I thought, oh I want to buy one of those. And my friend and I were just going to test ourselves. So I bought one and then it had space for 40 tests and so I thought, well I might as well just fill this whole thing up and run 40 tests and kind of get a better sense of how many people are positive because at the time it was unclear how far spread the virus had been.
So you are really, I think you might have been the first person who did an amateur or professional test of how many people had antibodies. Do you know if anybody tested before you?
No, as far as I know I was the first to report or I did publish the first report on a community kind of serum survey for COVID-19 antibodies.
Now you've been sort of paying attention to this little serum antibody thing and I know there was an article in The Wall Street Journal that said they had some small study, 39 people or something. And how did that go?
So yeah, we posted on this convalescent serum. I mean the idea of taking blood from somebody who's been infected and recovered and putting their antibodies in somebody else, what's the state of that in terms of the science? I know you're surveying the field there.
Yeah, so on Friday I believe the first convalescent serum therapy clinical study was published and the authors claim it was the first in the world published, or at least the largest. And so they did treat 39 patients like you said with convalescent serum therapy and it was controlled. So there was a group that did not receive that treatment and there was a significant improvement in survival with the group that did receive the convalescent serum therapy. There was about a 12.8 percent death rate for the convalescent serum therapy group but it was 24.4 percent for those who didn't receive it. So that means that the serum therapy cut the death rate in half and that was for people who were pretty close to death to begin with.
And I think I saw in the article that they just assumed it would work better if you had it earlier but it hasn't been tested. I guess now is there any reason to think that any of this would ever be dangerous? It doesn't go through, it wouldn't have to go, I know this is sort of outside your area, but I don't think this would have to go through the whole FDA approval because it's their antibodies. It's something we know well enough that we don't need to go through the whole thing, right?
Well it is actually FDA approved now, at least with an emergency use authorization. So that was one of the first things that became approved as a treatment for COVID-19 because it is generally safe. There's a couple of different things people generally test for like blood typing. You want to match the donor and recipient and then Rh factors. But other than that it appears to be safe.
So what would happen if you didn't match? Would it hurt you or would it just not help you? Suppose you had the wrong blood type match.
Yeah it could definitely hurt you down the road. It has been done without blood type matching. In fact when it was first used, the reports I've seen when it was first used are from the early 1900s and they were not doing blood type matching at that time but all those reports showed significant improvement.
Well if you had to guess based on, you know, isn't there two other cases where they've used this convalescent blood serum approach? Right, was it HIV was one?
Well I don't think it was used, or I'm not aware of it being used for HIV, but the treatment for HIV is monoclonal antibodies and same with Ebola. And so it's similar in a way because convalescent serum therapy is basically using antibodies. It's more of a kind of gross product of antibodies where you're just taking everything under the sun that's in somebody's serum and giving it to somebody else and you're not selecting for one specific antibody. But it has been used in SARS. There is actually a guy who got the 1901 Nobel Prize for the development of serum therapy. He solved a diphtheria epidemic in Germany in the 1890s by using serum therapies and that's kind of where it started. And so he's the pioneer in the field. His name's Emil von Behring.
Do you know what it would take to scale this up? Like let's say that in a few weeks we said yes this is the thing, we need more of this. Given that you have to actually take it from people unless you're using machines to clone it I guess, how quickly can, I know you did some calculations on how quickly you could scale up. What would you guess? I know this is an unfair question off the top of your head but let's say if we were to start today and say all right we want to get everybody convalescent blood serum therapy, like how close are we to being able to do that? Is that something that scales up very well?
I think that is generally reserved for the people that are in poor condition, in the hospital. So not everybody is going to need it but for those people it would be possible. It's obviously going to be dependent on your area. New York got hit so hard that I don't know if they would have been able to keep up with demand. But generally speaking you have about 5% of cases who end up in the ICU and those are the people that would be candidates to receive the therapy.
Would they really? Because why wouldn't you give it to people even before they have it so that if they did get it they could handle it more easily? Just because of scalability it is tough. You need to do plasmapheresis to get the plasma from donors. You also have to be checking people ahead of time to make sure that they actually had an antibody response against the virus.
Let me ask you some sort of detailed questions. If you're going to draw blood from one person and turn that one person's blood into antibodies, how long would the whole process take from putting the needle in to draw the blood to having it in your hand and ready to give somebody else?
I think that you can do plasmapheresis in a couple of hours. It depends obviously how much you're trying to harvest. The amount that the FDA allows I believe for a donation is a liter per week or two liters every two weeks. And then in the study that you were talking about they used about 500 milliliters which is a half a liter per patient. So it looks like if one donor giving one donation, over a two-week donation period, could handle two people.
One donation. If I donate blood once, how many people would that handle? So that's good. That's kind of hard to scale, isn't it?
Yes exactly. And so that's why I say it should be reserved for only the people that are in poor condition or in the hospital.
Now if you looked into the, I don't understand the differences or the nuances of monoclonal where you're just taking the best antibodies you can get from one real person and then you're cloning it with machines to scale it up. Is there a limit to how quickly you can do that if you just keep building machines? Couldn't we do a ventilator type thing where we just say all right everybody's building monoclonal devices? If you looked into those, do you know?
So they're not. Those are the first therapies that will come online for COVID-19 is monoclonal antibody therapies. It takes a little bit of time to develop because of the process. You build what are called hybridomas and that's a fusion between a cancer cell and an antibody creating cell and the cancer cell makes it immortal and then the antibody secreting cell is fused and it starts just producing antibodies en masse. And then you can create a ton of those cells. They're all identical and make a bunch of antibodies in a bioreactor and that's being done now. It just takes a little bit of time to identify the specific antibody secreting cell you want to use that's making good antibodies.
Now once you've identified the antibodies isn't it just a question of making more of those machines and more of those facilities? Couldn't you just keep scaling it up?
Definitely, correct. Yeah you could, especially if somebody identified a good antibody secreting cell and then made the hybridomas and if they were to share those with other people and kind of decentralize the production and make it scale faster that would maybe be a good way to do it. There's also, you should be probably combining a lot of different hybridomas to get good coverage for your antibodies, make sure that there's good protection there.
Have you heard, I haven't seen any news coverage of the monoclonal. Do you know if anybody's getting any traction actually doing that?
I haven't seen anything that's become available yet with those. I've seen some anecdotal reports about strong protection there. I think last week there was a report from a company that said they had a good candidate but it's still a little early. And the other thing is that there's a difference between having an antibody that you can see recognizes COVID-19 and then also whether that antibody neutralizes the virus. So I've actually seen some evidence in my hands where somebody can test positive for antibodies that recognize the virus but those antibodies don't necessarily neutralize the virus. And then conversely somebody could have a low level of antibodies that recognize the virus but those antibodies are very strong at neutralizing. So there is nuance there.
And do we have any more visibility on how long antibodies would last? Let's say you got them either naturally by having it and recovering or you got it from the plasma from somebody else. Do you know? Is there a difference in how long they would last?
That's a good question. I don't. You might expect there to be a shorter window for donor antibodies because they might start to get marked as non-self by your immune system and then kind of removed. But it's a tough thing to study because you start to get this mix of potentially antibodies made by yourself and antibodies from the donor and how do you differentiate which one came from which? But I think generally like two years is what a lot of people say. If you look at data from the original SARS patients, two years of protection is what people are getting at least. Some got protection out to seventeen years.
Now would you say that it comes down to literally just how fast we can make this stuff? I mean that's really the gating factor, right? Because at this point we kind of know it's safe and we kind of know it works or all common sense says it works. It would be hard to imagine it doesn't work.
Yeah it definitely works and one of the limitations is just getting access to the people who are producing those antibodies so that then you can kind of identify those antibody secreting cells and scale this. So I would encourage anybody that's ever had it and recovered to look into getting tested for antibodies and look into donating their serum for convalescent serum therapy because you could donate every week or every couple weeks and that serum can be banked for the future where maybe in the fall we have a second wave or something. So I think we should be stockpiling serum now in anticipation for the fall and winter.
Kind of interesting. So there's, I'd never heard before, which is we have all these strategic stockpiles of everything from oil to PPE and ventilators. It would make perfect sense to have a national stockpile of convalescent serum. That's actually a great idea. I hope somebody's watching this. We can do something about that.
Yeah, and that requires people who have had it to get tested for the antibodies and be kind of active participants. I think that a lot of people are looking for something that they can do to help nowadays and that's one pretty easy way to do it. And I think that those people should get paid to donate their serum. A lot of them have probably accrued pretty significant hospital bills along the way and this would be a way to offset those bills for them.
Now you're talking about how this might be a money-making thing. Are you aware of anybody who's ever charged for their antibodies for any kind of situation? Does that ever happen?
I'm not aware of a specific instance where somebody's donated their antibodies because they just had the greatest antibodies out there. But there's plasma donation centers all across the country. I don't know the name of one offhand but I know there's national chains of plasma donation centers and they pay people.
This is very interesting because the patriotic mood in the country at the moment is so high that you could get all the blood you wanted basically if the President of the United States said here's the deal, if you've tested positive I need you to go in and offer your blood. We're going to try to see how much we get. I believe that patriotism alone would give you all the blood you wanted. But if you really wanted to take it to the next level, people are people, and if you could offer more money to let's say go in a second or third or fourth time as you're suggesting, I would imagine that a monetary incentive would probably have a gigantic effect.
Yeah, and I've talked to some people about the monetary incentive and people get a little bit uneasy sometimes about that but my perspective is that it's going to be administered in the hospital and is the hospital making money? Yeah. So why shouldn't the donor?
Exactly. Now so we've got safety. It's really just a production problem it seems to me. And it's almost like gosh it feels like this is such a big deal. The biggest deal of course is wearing masks but I would think that the second most promising thing, if we have to wait for vaccines for months and months, the things that we can do now, the second most promising thing is probably this. What do you say?
In terms of things that we know that work and not having to wait around for something that may never actually happen. There's no guarantee that we'll have a vaccine or anything like that but we know this works and so why not embrace it while we also pursue other avenues to solve the problem.
I was just going to point out, so I started a company that we're going to be doing antibody testing as well and I'm specifically doing a neutralization test which means we're not just testing for the presence of antibody, we're testing to see whether your antibodies neutralize the virus. And we plan to take that data and publish the de-identified data on open source dashboards for anybody to check out just so everybody can get a general sense of where their community is in terms of relative protection. And then I plan on creating an avenue for people who test positive for neutralizing antibodies to be sent information on how to donate their plasma. So we'll be identifying those candidates and so then they should be told here's what you can do if you're interested in helping other people with your unique situation or unique set of antibodies.
So I've been watching the comments and I just want to call out something that I always talked about: winning attitudes and losing attitudes. And I'm watching a lot of losing attitudes in the comments, specifically people who don't quite appreciate, and I'm going to make them appreciate it now, the power of your talent stack. Because people are sort of saying, oh data analyst, what's that got to do with this? But the whole point is that you knew how to draw blood, you know how to get these tests, you've got what do you say your background was, a biological, bioscience. So he's got a bioscience background. So it basically compiled a whole bunch of skills together including starting a new business initiative to try to help with the coronavirus.
So what do you see? Ian jumping in and I was watching this from the beginning and on day one Ian was saying all right I have this talent stack, how can I help in this coronavirus thing? And then I've been watching as you've grabbed one piece at a time and tried to assemble it into something that would be bigger than the parts. And I've been completely impressed not only at the early data visualization stuff you're doing because initially you were doing data visualization, some of the best ones I've seen on the internet, and then you found that your talent stack gave you all the way to here and actually could be one of the pivotal at least informational parts of what would be the second most important thing we do after masks. So I'm very impressed at what you've done.
And for those of you who don't have the winning mindset, what the hell did you guys do? Let me just say that while you're out in the line to you limit to your tricks because there's always going to be somebody on the air, blah blah, I hear this all the time, hey you're a cartoonist, why are you doing this? But all of those people, you're not very successful I'll bet because if you're worried about staying in your lane and you're worried that people only have one talent, Ian's got more than one talent. Sorry if you only have one talent, maybe you don't understand how that works. But if you put enough talents together you have a superpower and I think this is a perfect example of it.
So Ian thank you for being a patriot and I mean that seriously because in times of crisis not everybody runs toward the fire and you did. On day one you were running toward the emergency. What can I do? And we need more of you and less of the people who are picking. I really appreciate that Scott and I just want to point out before I go that I can't do it all by myself. I have a lot of help from Mikkel Staten and Brianna Knight. They've been helping me get CureHub going and everything's about being on a team, a winning team, and we're all in this together and no one person can make anything work. And I think you've got to treat life like a positive sum game and then you'll start to find some wins all over the place.
Well that's something that's America in a nutshell right there. So thank you so much. Do you want to name a URL that you want people to look at?
Yeah you can go to cure-hub.com and we have a system in place where you can sign up and reserve your spot in line to get an antibody test and then you don't pay anything but you'll get on our mailing list and then as soon as we have the antibody tests approved which should be a couple weeks then we'll let you know and then you can join the study and donate a sample to get tested. We'll test you and yeah that's it.
All right so thank you. Thank you again. Thanks for being a great guest. I'm going to go on with the rest of my program and I'll catch up with you. Can I do one thing? I missed the simultaneous sip. Can I get another one live? I gotta do it. All right I will give you the first ever second simultaneous sip. And all you need is a cup, Ramona glass, tankard, any kind. You ready? Cheers. Cheers. The second simultaneous sip, even better than the first.
All right thanks again. Thank you. Bye.
All right so you know as much as the topic is interesting because in my opinion it's probably the most important topic besides masks, but I also wanted you to get a feel for Ian. You know just a feel for what your fellow citizens, if you're American, and I'm sure it's happening in every country around the world, people are just jumping into the breach and people are running toward this thing like crazy. When this is over, when this is over you're going to be really proud that you were a human because humans are pretty awesome and humans have done remarkable things in the past several months and there's a lot more to come. So we're all lost in the details and just trying to get through life and make it to the next time you can buy groceries and I know that that's got to be the focus but when this is done, when this is done there are going to be some real things to be proud about.
All right let's talk about some other things. I got a suggestion on the Locals platform where I've moved a lot of my non-Dilbert stuff. From Anholt, I don't know that's one name, and Nolt and Alt anyway I don't know his real name but he started referring to people who watched CNN and MSNBC as the poorly educated. How much do you love that? So I'm going to adopt that concept. So instead of what I used to be saying was you know it's two movies on one screen and some people are siloed in their news and they don't see the news from the other side and I used to sort of describe it in engineering terms but I thought this is so much more powerful. Just say it, oh you only watch these networks? Well you're among the poorly educated. Because it's literally just poorly educated which I think is hilarious because you know how much they can hate that.
So apparently in the polls, including a Fox News poll, Biden is ahead of Trump by way more than even Hillary was ahead of Trump at the same time. So apparently Biden is doing great by staying in his basement and just gaffing himself and decomposing at his basement. Now I don't know what could be more ridiculous or more funny than the fact that Joe Biden is in his basement. You literally just, you know, decomposing. And he stays at home and he just, are you ever just at home and you just are laughing about the whole Joe Biden in the basement situation? Because the Biden in the basement thing sort of crept up on us, right? Like it was like hey I think there's this virus and move on. All right yeah and yet it looks like it might be coming this way. All right and maybe we should stay away from public a little bit. And next thing you know a major candidate for president is living in his basement and babbling nonsense. And because we sort of got there gradually we've sort of accepted it.
Go on. Are you sure? Can you tell me that you've never just sat there by yourself and suddenly you just sort of realize the situation we're in with Joe Biden decomposing in his basement and leading in the polls to be the next president of the United States? I don't have his fingers on the nuclear button. If that's not funny to you it is. But here's the thing that's funniest. I'm not positive so don't hold me to this later. I'm not positive but I think we might be witnessing the greatest practical joke of all time. And what I mean by the greatest practical joke is I think, I can't prove this, I think conservatives are massively lying to pollsters because it's funny. Tell me I'm wrong. Don't you sort of suspect? Because if you were saying to yourself okay I get that President Trump's not popular and all the Democrats are going to vote for whoever the Democrat is, yeah I get that. That's going to explain most of what you see. But the fact that Biden's down there decomposing and leading the polls strongly suggests that what we're seeing is a really large national scale practical joke. Because if the polls still say Biden by eight points and then Trump wins by eight points it's going to be the greatest troll of all time. Honestly it will be the most epic practical joke ever played in the history of practical jokes and I think that's what's happening. Am I wrong? Am I completely off base? Because I'm seeing a lot of people in the comments who are saying I think you're right. I think the Republicans are just lying to the pollsters because it's funny.
Speaking of funny pranks, Alyssa Milano got photographed wearing a crochet mask and you can imagine how the internet reacted to her crochet mask. They of course said hey there are holes in your crochet therefore you fool, you idiot, you dumb Democrat, you Biden supporting fool. How could you wear a crochet mask? And worse yet if you're going to wear a crochet mask don't get your photograph taken if you're famous. And so of course Twitter went on fire. It's like she doesn't know anything, you idiot, your crochet mask. And then Alyssa Milano waited. Wait hold hold hold. And then it was, Alyssa Milano tweets to one of her critics, carbon filter inside. Love it. It was a trap. It was a trap. Do you think she knew that people were going to go after her crochet mask? Which she says, and I think it's probably true, she says has a carbon filter on the inside. It probably does because if you've got those good N95 masks they're the ugliest of the masks. So if she figured out a way to put a more pleasant cover over the ugliest mask which is also the best kind of mask, maybe. I don't know if it was an N95 but she said a carbon filter so maybe that's good too.
All right if you're not watching, I've said this a million times but if you're not following Mike Cernovich on Twitter you're missing one of the best shows. It's like a TV show that just goes on all the time. It doesn't have a beginning or an end. Like every time I get on Twitter I see like five Cernovich quotes and everyone does it makes you stop and go huh. But this one, if you want to understand how to operate on the next level, this tweet from Cernovich made me laugh for two days. If this is the whole tweet he goes, self-confidence triggers mediocre man. Now of course the beauty of it is you can't complain about it without being labeled the mediocre man. So it's like this perfect little trap. It's like I want to complain about that because I'm really mad about your self-confidence but if I do complain about it does that make me a mediocre man? So watching Cernovich build these little Twitter traps for the mediocre man, that's one of the funniest things I've seen on the internet.
Telehealth has taken off. I said this before but there's even more signs of it. Have you seen all the commercials? Telehealth is basically just huge now. We thought that might happen but apparently it is happening. The lasting benefit we're going to get from telehealth is going to be gigantic and the ability to practice across state lines which I think will become permanent would be huge. And again thank you to all of you who helped make that happen. So just checking in on that because it's such a big topic and it's going in the right direction so it's always good to hear some good news.
All right what else we got going here? There's some kind of drug called ivermectin that's getting some good reviews and I guess it can interact with other medications and has some side effects and stuff but there were some initial trials that sort of look good. So ivermectin. There's another one. I think that over the next few weeks you're just going to hear one therapeutic after another and it's just going to be all positive news.
Now if you've done the math, I did this last night in Periscope, I was talking about all the things which have cut the risk down. So masks are supposed to be 75 percent effective. Distance of course is completely effective. Maybe vitamin D. Maybe summer will make a difference in the warm weather. Maybe what we've learned about nursing homes and how to protect them. Maybe what we've learned about ventilator use not to kill people with ventilators. If you take each of these many pieces of good news, each of them individually reduces risk by some percentage from 75% with masks down to maybe vitamin D makes a difference or maybe it's just correlation we don't know if it's causation yet but maybe hydroxychloroquine and zinc if you get it early maybe 20% benefit. Maybe there's some people we can get with this convalescent blood serum. So we now have off the top of my head maybe 10 to 12 different things we've either developed as tools or learned which also allows us to reduce risk. I feel like we have all the tools to within a few weeks we're going to have the risk down to, it's going to approach zero. I mean it's almost going to disappear. I think monoclonal antibodies, almost ready somebody says yeah and that could be huge. The monoclonal antibodies just could be huge.
All right and then somebody says primarily immune system strength. Let me ask you this. I want to see this in the comments. When this whole thing started I was advising everybody to just make sure they took care of their immune system. So in other words get a little light exercise, get some sun, get some sleep, all the usual things. How many of you have done that? How many of you in the comments, it'll take a little time to load here but in the comments tell me if you feel that you've done something that would boost your immune system. Have you intentionally boosted your immune system? With all the yeses. Wow almost every person, every so far every person who's answering is saying yes. Think about that. What kind of change does that make in your life and in civilization if suddenly 370 million people just decided to get serious about boosting their immunity and their health? Oh my god I am so impressed.
For those of you who are listening to this it is a non-broken string of yeses. I've never seen so much agreement. Somebody lost 20 pounds bicycle riding outdoors. Yes definitely. Yes yes yes yes. Immune system way up. Yes. Oh my goodness I am so so impressed. Very impressed. I've never seen anything like this. Are you as impressed as I am? Take a look at these comments coming by. They're still absolutely solidly yes. Holy cow this is one of the, this is the most underreported story of the year isn't it? Wouldn't you say this is the most underreported story? If we had not had a coronavirus and suddenly you found that 370 million Americans and I'm guessing other countries doing something similar, if you found that hundreds of millions of people suddenly took seriously their health, what did we just do to the entire health care cost of this country? How much of this is going to become habit?
You know I'm wondering if you think that you'll be able to turn this into habit. The trouble is a lot of us not going to work in the normal ways. We don't have the normal schedule so it's going to be harder when you're trying to work it in with your normal schedule. But wow I am so impressed with all of you. Genuinely. Somebody stopped smoking. Congratulations. Congratulations on stopping smoking. That is hard.
All right so well that might be the good news for this. Maybe our healthcare cost just took a 20% hit simply because we're in better shape and we know how to do this. So where can you outdoors shoot? I don't understand that question.
All right well I'm impressed with you all and I'm going to leave you on that note. Hope you learned something today and I'll talk to you tonight.
um did you wonder where I was I'm two minutes late I couldn't get my Wi-Fi working a little power outage last night s things up but I'm good now or back and that means it's time for a little thing you call simultaneous it I call it that too and all it takes is a cup of mud or a glass of tanker gels to design a Kent injector flies got vessel of any kind hello with your favorite liquid I like coffee and join me now for the unparalleled pleasure the dopamine the end of the day the thing that makes everything better including the damn pandemic it's called the simultaneous if and it happens now go mmm now if you joined us last night I had a little technical difficulty I was trying to bring on a special guest to talk about convalescent blood serum and as soon as he's ready we're gonna try that again this morning so I'll wait to wait till see when Ian gets on all right let's tell him we're good now in the news my favorite story is that President Trump apparently wanted to go golfing this weekend Behati didn't want it to be the biggest story so what do you do if you want to go golfing and you're the president and you don't want it to be the biggest story for three days well on the way out the door to golf what you do is you to send a tweet that accuses Joe Scarborough of murder they have to appreciate how much fun that is now of course now for the family of the victim who died many years ago but the fact that Trump would accuse somebody of murder before he goes golfing is beautiful so I see Ian as joined so let me just finish the story a little Adam on now here's my take of that now on one hand it's completely outrageous and inappropriate that the President of the United States would accuse Joe Scarborough of murder when there's no indication that he actually murdered anybody there was some young woman who hit her head and died in his office years ago now that's all we know and she had some health problem that suggests that she just passed out yet but the fact that the president would say that now you say to yourself well that's all wrong that is so wrong that is wrong on a level that's deeper than any wrongness except except we are talking about Joe Scarborough who did lie about the president in the worst possible way for years I believe he accused the president of suggesting people should drink bleach that never happened I think he suggested the President had called neo-nazis in Charlottesville fine people that never happened so is it fundamentally different to accuse somebody of being pro-nazi versus saying you murdered your girlfriend they're not that different really because once you have accepted that you can say absolutely anything in the political context there's just no penalty you can say absolutely anything the president just took the rules and said what are the rules of the rules are you can say anything really just anything I can just make up anything and I can just say it public and it's a headline all right how about joe scarborough's a murderer we'll see how that goes went pretty well all right let's see if we get Jana Ian on the line this will be a test of the technology I think we got it I think we got it Oh seriously because I know we had a Wi-Fi problem yesterday and it looks like we got a Wi-Fi problem today well whatever the problem is doesn't look like that's gonna get solved I'll try it one more time but then I think we should maybe give up on this if it doesn't work this time yeah and we'll try you one more time yeah hey let's make this work the this is the first time the technology has worked more than five seconds so I feel good about it that's a good sign all right good strong signal all right Ian first of all let me see if I can pronounce your name correctly Ian Hill guard Martius pretty close yes yes you nailed it all right can you tell the audience what your background is and how that relates specifically to the convalescent blood plasma testing situation give them a little background on you okay so my background is that I worked in bioscience for about ten years and then I ended up kind of leaving academic bioscience and taught myself to program and become a data analyst and started working in corporate and for a corporation as a data analyst and when the co good stuff started to hit I would figure out ways to harvest public data to do public data analysis that I could publish so to help people understand the situation a little better and then through that process I started to you know think about different answers that I thought we needed that maybe we weren't getting from the media and one of the things I thought about as well as you know what can we do now what can we do before there's a vaccine because there's going to be people who can't wait that long and the development of new therapeutics that takes so long that a lot of people would end up dying while they wait and so you know we got to figure something out in the middle so tell us what you did because I was I was sort of following the law early on and and you put together your own tests right well it wasn't necessarily my own test I bought a commercially available test kit I just happened to become aware of its existence pretty early I suppose in the way that I became aware of it is that I just got like a spam email because you know when you buy something from a vendor they put you on a mailing list and then they always blast out these kind of spam advertisements and so I got one of those that said oh hey we have these Ovid 19 antibody tests and so I thought oh I want to buy one of those and my friend and I were just going to test ourselves so we so I bought one and then it had space for 40 tests and so I thought well I might as well just fill this whole thing up and run 40 tests and kind of get a better sense of how many people are positive because at the time it was unclear of how far spread the virus had been so so you are really I think you might have been the first person who did and an amateur or professional test of how many people had antibodies do you know anybody tested before you know I as far as I know I was the first report or I did publish the first report about or on a community kind of serum survey for over nineteen antibodies now so you've been sort of paying attention his little serum antibody thing and I know there was a there was a article in The Wall Street Journal that said they had some small 39 people or something and how did that go so yeah we positive on this convalescence Europe I mean the idea of taking blood from somebody who's been infected and recovered and putting their antibodies and somebody else what's the state of that in terms of the science I know you're surveying the field there yeah so on Friday I believe the first convalescent serum therapy clinical study was published in the authors claim it was the first in the world publish or at least the largest and so they did treat 39 patients like you said with convalescence serum therapy and it was controlled so there was a group that did not receive that treatment and there was a significant improvement in survival with the group that did receive the convalescent serum therapy there was about twelve point eight percent death rate for the convalescent serum therapy group but it was twenty four point four percent for those who didn't receive it so that means that the serum therapy cut the death rate in half and that was for people who were pretty close to death to begin with and I think I saw in the article that they they just assumed it would work better if he had it earlier but hasn't been tested I guess now is there any reason to think that any of this would ever be dangerous does it it doesn't go through it wouldn't have to go I know this is sort of outside your area but I don't think this would have to go through whole FDA with it the whole FDA approval because it's their antibodies is something we know well enough that we don't need to go through the whole tastic well well it is actually FDA approved now at least with an emergency use authorization so that was one of the first things that became approved as a treatment for carbon 19 because it is generally safe there's a couple of different things people generally test for like blood typing you want to match the donor and recipient and then Rh factors but other than that it appears to be safe so if well what would happen if you didn't match wouldn't hurt you or would it just not help you suppose you had the wrong blood type match yeah it could it could definitely hurt you down the road I'm not you know it has been done without blood type matching in fact when it was first used or the reports I've seen when it was first users from the early 1900's and they were not doing blood type matching at that time but all those reports showed significant improvement well well if you had to guess based on you know isn't there there are two other cases where they've used this convalescent blood serum approach right was it HIV was one well I don't think it was used or I'm not aware of it being used for HIV but the treatment for HIV is monoclonal antibodies and same with Ebola and so it's similar in a way because convalescent serum therapy is used basically using antibodies it's more of a kind of gross product of antibodies where you're just taking everything under the Sun that's in somebody's serum and giving it to somebody else and you're not selecting for one specific antibody but it has been used in SARS there is actually a guy who got the 1901 Nobel Prize for the development of Serapis in he solved diphtheria epidemic in Germany in the 1890s by using serum therapies and that's kind of where it started and so he's the pioneer in the field his name's Emil von Behring oh do you do you know what it would take to scale this up like let's say that in a few weeks we said yes this is the thing we need more of this given that you have to actually take it from people unless you're using machines to clone it I guess how quickly can I know you did some calculations on how quickly you could scale up well what what would you guess I know this is an unfair question off the top of your head but let's say if we were to say start today and said all right we want to get everybody kind of lesson blood serum therapy like how close are we to being able to do that is that something that scales up very well um I think that is generally reserved for the people that are in poor condition you know in the hospital so not everybody is gonna need it but for those people it would be possible I is obviously gonna be dependent on your area New York got hit so hard that I don't know if they would have been able to keep up with demand but generally speaking you have about 5% of cases who end up in the ICU and those are the people that would be candidates to receive the therapy would they really because why wouldn't you give it to people even before they have it so that they if they did get it they could handle it more easily just because of scalability it is tough you need to do on plasmapheresis to get the plasma from donors you also have to be checking people ahead of time to make sure that they actually had an antibody response against the virus let me ask you some sort of detailed questions if you're gonna draw blood from one person and turn that one person's blood into antibodies how long with the whole process take from putting the needle in to draw the blood to to having it in your hand and ready to give somebody else I think that you can do quest my paresis in a couple of hours it depends on obviously how much you're trying to harvest the amount that the FDA allows I believe for a donation is a liter per week or two liters every two weeks and then in the study that you're taught you were talking about they used about 500 milliliters which is a half a liter per patient so it looks like I don't lift it you don't need go ahead it did to simplify that each donor giving one donation could handle how many people for it looks like if over a 2-week donation period or two Huffer one one donation if i donate blood once how many people would that handle to say oh that's good that's kind of hard to scale isn't it yes exactly and so that's why I say it should be reserved for only the people that are in poor condition or in the hospital now if you looked into the I don't understand the the differences or the nuances of monoclonal where you're just taking you know the best antibodies you can get from one real person and then you're cloning it with machines to scale it up it is is there a limit to how quickly you can do that if you just keep building machines you couldn't could we do a ventilator type thing or we just say all right everybody's building monoclonal devices if you looked into those do you know yeah so that they're not yeah those are the first therapies that will come online for carbon 19 is that monoclonal antibody therapies it takes a little bit of time to develop because of the process you build what are called hybridomas and that's a fusion between a cancer cell and an antibody creating cell and the cancer cell makes it immortal and then the antibody secreting cell is fused and it starts just producing antibodies and mass and then you can create a ton of those cells they're all identical and make a bunch of antibodies in a bioreactor and that's being done now it just takes a little bit of time to identify the specific antibody secreting cell you want to use that's making good antibodies now what once you've identified the antibodies isn't it just a question of making more of those machines and more of those facilities couldn't couldn't you just keep scaling it up and definitely correct yeah you could especially if you know you somebody identified a good antibody secreting cell and then made the hybridomas and if they were to share those with other people and kind of decentralize the production and make it scale faster that would maybe be a good way to do it there's also you know you should be probably combining a lot of different hybridomas to get good coverage for your antibodies make sure that they're there's a good protection there do you have you heard I haven't seen any news coverage of the monoclonal anything didn't do you know if anybody's getting any traction actually doing that I haven't seen anything that's become available yet with those I've seen some anecdotal reports about strong protection there I think last week there's a report from a company that said they had a good candidate but you know it's still a little early and the other thing is that there's a difference between having an antibody that you can see recognizes Kovan 19 and then also whether that antibody neutralizes the virus so I've actually seen some evidence in my hands where somebody can test positive for antibodies that recognize the virus but those antibodies don't necessarily neutralize the virus and then conversely somebody could have a low level of antibodies that you know recognize the virus but those antibodies are very strong at neutralizing so there is no off there so and do we have any more visibility on how long antibodies would last let's say you got them either naturally by having it recovering or you got it from from the plasma from somebody else do you know Israeli difference and how long they would last you know that that's a good question I don't you might expect there to be a shorter window for donor antibodies because they might have start to get marked as non-self by your immune system and then kind of removed but it's a tough thing to study because you know you start to get this mix of potentially like antibodies made by yourself and antibodies from the the donor and how do you differentiate which one came from which but I think generally like two years is what a lot of people say if you look at data from the original SARS patients two years of protection is what people are getting at least so I'm at least some got protection out to seventeen years so now would what do you say that it comes down to literally just how fast we can make this stuff I mean that's really the gating factor right because at this point we kind of know it's safe and we kind of know it works or all common sense says it works right I mean it would be hard to imagine it doesn't work yeah yeah it definitely works and one of the limitations is just getting access to the people who are producing those antibodies so that then you can kind of identify those antibody secreting cells and scale this so I would encourage anybody that's ever had it and recovered to look into getting tested for antibodies and look into donating their serum for a convalescence serum therapy because every you could donate every week or every couple weeks and that serum can be banked for the future where maybe in the fall we have a second wave or something so I think we should be stockpiling serum now I'm in anticipation for the fall and winter kinda interesting so there's there's I'd never heard before which is we have all these strategic stockpiles of everything from oil to PPE and ventilators it would make perfect sense stuff a national stack the stockpile temporarily I don't know how long you can store this stuff but it would that makes perfect sense of a national stockpile of convalescence Europe that's actually a great idea I hope somebody's watching this we can do something about that yeah yeah good yeah and that like I said requires people who have had it to get tested for the antibodies and be kind of active participants I think that a lot of people are looking for something that they can do to help nowadays and that's one pretty easy way to do it and you know I I think that those people should get paid to donate their serum a lot of them have probably accrued pretty significant hospital bills along the way and this would be a way to offset those bills for them and oh yeah oh now you now you're this is interesting so you're talking about how this might be a money-making thing are you aware of anybody who's ever charged for their antibodies for any kind of situation does that ever happen I'm not aware of a specific instance where somebody's donated their antibodies because they just had greatest antibodies out there but you know there's plasma donation centers all across the country I don't know the name of one offhand but I know there's national chains of plasma donation centers and they pay people the this is very interesting because you know I I think that the patriotic mood in the country at the moment is so high that you could get all the all the blood you wanted but basically if the if the President of the United States said here's the deal if you've tested positive I need you to do this go in and offer your blood we're gonna try to see how much where you get I believe that patriotism alone would give you all the blood you wanted but if you really wanted to take it to the next level people are people and if you could offer more money to let's say go in in time or the third or fourth time as you're suggesting I would imagine that a monetary incentive would probably have a gigantic yes yeah yeah and I I've talked to some people about you know the monetary incentive and people get a little bit uneasy sometimes about that but my perspective is that you know it's going to be administered in the hospital and is the hospital making money yeah so why shouldn't I don't yeah exactly now so we've got safety it's really just a production problem it seems to me and it's almost like gosh it feels like this is such a big deal you know every the the biggest deal of course is wearing masks but I would think that the second most promising thing you know if we have to wait for vaccines for months and months but the things that we can do now the second most promising thing is probably this what do you say yeah in terms of things that we know that work and not having to wait around for something that you know may never actually happen right we there's no guarantee that we'll have a vaccine or anything like that but we know this works and so you know why not embrace it well we also pursue other avenues to solve the problem so that is yeah good I was just going to point out so I started a company that we're going to be doing antibody testing as well and I'm specifically doing a neutralization tests which means we're not just testing for the presence of antibody we're testing to see whether your antibodies neutralize the virus and we plan to take that data and kind of publish it on publish the de-identified data on open source dashboards for anybody to check out just so everybody can get a general sense of where their community is in terms of relative protection and then I plan on creating an avenue for people who test positive for neutralizing antibodies to be sent information on how to donate their plasma right so we'll be identifying those candidates and so then they should be told you know here's what you can do if you're interested in helping other people with your unique situation or unique set of antibodies so I've been watching the comments and I just I just want to call out something that I always talked about winning attitudes and losing attitudes and I'm watching a lot of losing attitudes in the in the comments specific specifically people who don't quite appreciate and I'm gonna make them appreciate it now the power of your talent stack because people are sort of saying oh data analyst what's that got to do with this but the whole point is that you knew how to draw blood you know how to get these tests you've got what do you say your background was a biological what by bioscience yeah so he's in a bioscience background so it basically compiled a whole bunch of skills together including starting a new business initiative to try to help with the coronavirus so what do you see Ian jumping in and I was watching this from the beginning and on day one Ian was saying alright I have this at a talents how can I help in this coronavirus thing and then I've been watching as you've you've you've grabbed you know like one piece of one piece of it at a time and tried to assemble it into something that would be bigger than the parts and I've been I've been completely impressed not only at the early data visualization stuff you're doing because initially you were doing data visualization some of the best ones I've seen on the internet and then you found that your talent stack gave you all the way to here and actually you know there you know it could be a you know one of the pivotal at least informational parts of what would be the second most important thing we do after masks so I'm very impressed at why you've done and for those who are we don't have the winning mindset what the hell did you guys do let me just say that while you're out in the line to you limit to your tricks because because you know there's always going to be somebody on the air blah blah I hear this all you know hey you're a cartoonist why you do this little lot but all of those people you're not very successful I'll bet because if you're worried about staying in your lane and you're worried that people only have one Talent Ian's got more than one Talent sorry if you only have one Talent maybe you don't understand how that works but if you put enough talents together you have a superpower and I think this is a perfect example of it so Ian thank you for being a a patriot and I mean that seriously because in in times of crisis not everybody runs toward the fire and you did you know on day one you were running toward the emergency you know what can I do and we need more of you and less of the people who were picking I I really appreciate that Scott and I just want to point out before I go that I can't do it all by myself I have a lot of help from Mikkel Staten and Brianna Knight they've been helping me get cure hub going and you know it everything's you know about being on a team and winning team and you're we're all in this together and no one person can make anything work and I think it's you gotta treat life like a positive sum game and then you'll start to find some yes all over the place well that's something that's America in a in a nutshell right there so thank you so much do you want to name a URL that you want people look at yeah you can go to cure - hub calm and we have a system in place where you can sign up and get reserve your spot in line to get antibody test it and then you don't pay anything but you'll get on our mailing list and then as soon as we have the antibody tests approved which should be a couple weeks then we'll let you know and then you can join the study and you know donate a sample to get tested we'll test you and yeah that's all right so thank you thank you again thanks for being a great guest I'm gonna go on with the rest of my program and I'll catch up with you can I do one thing I miss the simultaneous sip can I get another one live I gotta do it all right I will give you the the first ever second simultaneous sip and all you need is a cup Ramona glass tank any kind you ready cheers Cheers the second simultaneous sip even better than first all right thanks again thank you bye all right so you know I as much as that the topic is interesting because in my opinion is probably the most important topic besides masks but I also wanted you to get get a feel for Ian you know just just to feel for what you are fellow citizens if you're American and I'm sure it's happening in every country around the world people are just jumping into the breach any people are running toward this thing like crazy you know when this is over when this is over you're gonna be really proud that you were a human because humans are pretty awesome and and and humans have done remarkable things in the past several months and there's a lot more to come so you know we're all lost in the details and just trying to get through life and you make it to the next time you can buy groceries and I know that that's got to be the focus but when this is done when this is done there gonna be some real real things to be proud about all right let's talk about some other things I got a suggestion on the locals platform where I've moved a lot of my non Dilbert stuff from Anholt I don't know that's one name and Nolt and alt anyway I don't know his real name but he started referring to people who watched CNN and MSNBC as the poorly educated how much do you love that so I'm gonna I gonna adopt that that concept so instead of what I'd be what I used to be saying was you know it's two movies on one screen and some people are siloed in their in their news and they don't see the news from the other side and I used to sort of describe it as you know in engineering terms but I thought this is so much more powerful just say it oh you only watch these networks well you're among the poorly educated because it's literally jus literally poorly educated which i think is hilarious cuz you know how much they can hate that so apparently in the in the polls including a Fox News poll Biden is ahead of Trump by way more than even Hillary was ahead of Trump at the same time so apparently Biden is doing great by staying at a public and just gaffing himself and decompressing at his basis now I don't know what could be more ridiculous or more funny than the fact that Joe Biden is his basement you literally just you know decomposing and he and he sees what great honestly are you ever just a home and he just are laughing about the whole Joe Biden in the basement situation because you know the the Biden and the basement things sort of crept up on us right like it was like hey I think there's this virus and move on all right yeah and yet in like it looks like it might be coming this way all right and maybe we should you know stay away from public a little bit and next thing you know a major candidate for president is living in his basement and babbling nonsense and be and because we sort of got there gradually we've sort of accepted it go on are you are you sure uh-huh can you tell me that you've never just you just sit there by yourself and suddenly you just sort of realise the situation we're in would Joe Biden decomposing in his basement and leading leading in the polls to be the next president of the United States I don't have his fingers on the nuclear on the nuclear button if that's not funny to you it is but here's the thing that's funniest I'm not positive so you know you can't you know don't hold me to this later I'm not positive but I think I just think we might be witnessing the greatest practical joke of all talk and what I mean by the greatest practical joke is I think I can't prove this I think conservatives are massively lying to pollsters because it's funny right dude tell me I'm wrong don't you don't you sort of suspect because if you were saying to yourself okay I get that president Trump's not popular and you know all the Democrats are gonna vote for whoever the Democrat is yeah I get that you know that's gonna explain most of what you see right but the the fact that Biden's down there decomposing and leading the polls strongly suggests it strongly suggests that what we're seeing is a really large national scale practical joke because if the if the polls still say Biden by eight points and then Trump wins by eight points it's going to be the greatest troll of all time honestly it will be it will be the most epic practical joke ever played in the history of practical jokes and I think that's what's happening am I wrong get am i completely off-base because I'm seeing a lot of people in the comments were saying I think you're right I think you're right I think the Republicans are just lying to the pollsters because it's funny speaking of funny pranks Alyssa Milano got photographed wearing a crochet mask and you can imagine how the internet reacted to her crochet mask they of course said hey there are holes in your crochet therefore you fool you idiot you dumb Democrat you bite in supporting fool you fool how could you wear a crochet map mask and worse yet if you're gonna wear a crochet mask don't get your photograph taken if you're famous and so of course Twitter went on fire it's like doesn't know anything you idiot your crochet bass and then Alyssa Milano waited wait hold hold hold and then it was ylim Alyssa Milano tweets to one of her critics carbon filter inside love it was a trap it was a trap do you think she knew that people were gonna get out or about her crochet mask which she says and you know I think it's probably true she says as a carbon filter on the inside it probably does probably does because if you've got those good n95 masks they're the ugliest of the masks so if she figured out a way to put a you know a more pleasant cover over the ugliest mask which is also the best kind of mask maybe maybe I don't know if it was an n95 but she said a carbon filter so maybe that's good - all right if you're not watching I've said this a million times but if you're not following Mike's or a on Twitter you're missing one of the best shows it's like it's like a TV show that just goes on all the time it doesn't have a beginning or an end like every time every time I get on Twitter I don't see like five certain if it's quotes and everyone does it makes you stop and go huh but this one if you want to understand how to operate on the next level this this tweet from sorry this made me laugh for two days if this is the whole tweet he goes self-confidence triggers mediocre man now of course the beauty of it is you can't complain about without being labeled the mediocre man so it's like this perfect little trap it's like I want to complain about that because I'm really mad about your self-confidence I'm like sort of but if I do complain about it does that make me a mediocre man so yeah watching sort of itch build these little Twitter traps for a mediocre man that's one of the funniest things I've seen on the Internet telehealth has taken off I said this before but there's even more signs of it have you seen all the commercials telehealth is basically just huge now we thought that might happen but apparently it is happening the the last thing benefit we're gonna get from telehealth it's gonna be gigantic and the ability to you know practice across state lines which i think will become permanent would be huge and again thank you to all of you who helped make that happen so that's just checking in on that because it's such a big topic and it's go in the right direction so it's always good to hear some good news all right what else we got going here there's some kind of drug called ivermectin that's getting some good reviews and I guess it it can interact with other medications and has some side effects and stuff but there were some initial trials that you know sort of look good so I've heard nekton there's another one I think that in the next over the next few weeks you just gonna hear one therapeutic after another and it's just gonna be all positive news now if you've done the math I did this last night in periscope I was talking about all the things which have cut the wrists down so masks are supposed to be 75 percent effective distance of course is completely effective maybe vitamin D maybe summer will make a difference in the warm weather you know maybe what we've learned about nursing homes and how to protect them maybe what we've learned about ventilator use not to kill people with ventilators if you if you take each each of these many pieces of good news each of them individually reduces risk by some percentage from 75% with masks down to maybe vitamin D makes a difference or maybe it's just correlation we don't know if it's causation yet but maybe hydroxychloroquine and zinc if you get a Merlin he's 20% benefit maybe there's some people we can get with this convalescent blood serum so we now have off the top of my head maybe 10 to 12 different things we've either developed as tool or learned which also allows us to reduce risk I feel like we have all the tools to within a few weeks we're gonna have the risk down to it's gonna approach to zero I mean it's almost gonna disappear I think monoclonal antibody is almost ready somebody says yeah and that could be huge the monoclonal antibodies just could be huge all right and then somebody says primer primarily immune system strength let me ask you this I want to see this in the comments when when this whole thing started I was advising everybody to just make sure they took care of their immune system so in other words you know get out get a little light exercise get some Sun get some sleepy right you know all the usual things how many of you have done that how many of you in the comments it'll take a little time like here but in the comments tell me if you feel that you've done something that would boost your immune system have you have you intentionally boosted your immune system with all the yeses Wow almost every person every so far every person who's answering you saying yes think about that well what kind of what kind of change does that make in your life and in civilization if suddenly 370 million people just decided to get serious about boosting their immunity and their health oh my god I am so impressed uh for those of you who are listening to this it is a non broken string of yeses I've never seen so much agreement somebody lost 20 pounds bicycle riding outdoors yes definitely yes yes yes yes immune system way up yes oh my goodness I am so so impressed very impressed I've never seen anything like this are you as impressed as I am take take a look at these comments coming by they're still absolutely solidly yes holy cow this is one of the this is the most underreported story of the year isn't it wouldn't you say this is the most underreported story if if we had not had a corona virus and suddenly you found that 370 million Americans and I'm guessing other countries doing something similar if you found that you know hundreds of millions of people suddenly took seriously their health what did we just do to the entire health care cost of this country how much of this is going to become habit you know I'm wondering if you think that you'll be able to turn this into habit the trouble is you know a lot of us not going to work in the normal ways we don't have the normal schedule so it's gonna be harder when you're trying to work it in with your normal schedule but wow I am so impressed with all of you genuinely somebody stopped smoking congratulations congratulations on stopping smoking that is hard alright so well that might be the good news for this may be our healthcare cost just took 20% hit simply because we're we're in better shape and we know how to do this so where can you outdoors shoot I don't understand that question all right well I'm impressed with you all and I'm gonna leave you on that note hope you learned something today and I'll talk to you tonight
um did you wonder where I was I'm two
minutes late
I couldn't get my Wi-Fi working a little
power outage last night s things up but
I'm good now or back and that means it's
time for a little thing you call
simultaneous it I call it that too
and all it takes is a cup of mud or a
glass of tanker gels to design a Kent
injector flies got vessel of any kind
hello with your favorite liquid I like
coffee
and join me now for the unparalleled
pleasure the dopamine the end of the day
the thing that makes everything better
including the damn pandemic it's called
the simultaneous if and it happens now
go mmm
now if you joined us last night I had a
little technical difficulty I was trying
to bring on a special guest to talk
about convalescent blood serum and as
soon as he's ready we're gonna try that
again this morning so I'll wait to wait
till see when Ian gets on all right
let's tell him we're good now in the
news my favorite story is that President
Trump apparently wanted to go golfing
this weekend
Behati didn't want it to be the biggest
story so what do you do if you want to
go golfing and you're the president and
you don't want it to be the biggest
story for three days well on the way out
the door to golf what you do is you to
send a tweet that accuses Joe
Scarborough of murder
they have to appreciate how much fun
that is now of course now for the family
of the victim who died many years ago
but the fact that Trump would accuse
somebody of murder before he goes
golfing is beautiful so I see Ian as
joined so let me just finish the story a
little Adam on now here's my take of
that now on one hand it's completely
outrageous and inappropriate that the
President of the United States would
accuse Joe Scarborough of murder when
there's no indication that he actually
murdered anybody there was some young
woman who hit her head and died in his
office years ago now that's all we know
and she had some health problem that
suggests that she just passed out yet
but the fact that the president would
say that now you say to yourself well
that's all wrong that is so wrong that
is wrong on a level that's deeper than
any wrongness except except we are
talking about Joe Scarborough who did
lie about the president in the worst
possible way for years I believe he
accused the president of suggesting
people should drink bleach that never
happened I think he suggested the
President had called neo-nazis in
Charlottesville fine people that never
happened
so is it fundamentally different to
accuse somebody of being pro-nazi versus
saying you murdered your girlfriend
they're not that different really
because once you have accepted that you
can say absolutely anything in the
political context there's just no
penalty you can say absolutely anything
the president just took the rules and
said what are the rules of the rules are
you can say anything really just
anything I can just make up anything and
I can just say it
public and it's a headline all right how
about joe scarborough's a murderer we'll
see how that goes
went pretty well all right let's see if
we get Jana Ian on the line this will be
a test of the technology I think we got
it
I think we got it Oh seriously because I
know we had a Wi-Fi problem yesterday
and it looks like we got a Wi-Fi problem
today well whatever the problem is
doesn't look like that's gonna get
solved I'll try it one more time but
then I think we should maybe give up on
this if it doesn't work this time
yeah and we'll try you one more time
yeah hey let's make this work the this
is the first time the technology has
worked more than five seconds so I feel
good about it
that's a good sign all right good strong
signal all right Ian first of all let me
see if I can pronounce your name
correctly
Ian Hill guard Martius pretty close yes
yes you nailed it all right can you tell
the audience what your background is and
how that relates specifically to the
convalescent blood plasma testing
situation give them a little background
on you okay so my background is that I
worked in bioscience for about ten years
and then I ended up kind of leaving
academic bioscience and taught myself to
program and become a data analyst and
started working in corporate and for a
corporation as a data analyst and when
the co good stuff started to hit I would
figure out ways to harvest public data
to do public data analysis that I could
publish so to help people understand the
situation a little better and then
through that process I started to you
know think about different answers that
I thought we needed
that maybe we weren't getting from the
media and one of the things I thought
about as well as you know what can we do
now what can we do before there's a
vaccine because there's going to be
people who can't wait that long
and the development of new therapeutics
that takes so long that a lot of people
would end up dying while they wait and
so you know we got to figure something
out
in the middle so tell us what you did
because I was I was sort of following
the law
early on and and you put together your
own tests right
well it wasn't necessarily my own test I
bought a commercially available test kit
I just happened to become aware of its
existence pretty early I suppose in the
way that I became aware of it is that I
just got like a spam email because you
know when you buy something from a
vendor they put you on a mailing list
and then they always blast out these
kind of spam advertisements and so I got
one of those that said oh hey we have
these Ovid 19 antibody tests and so I
thought oh I want to buy one of
those and my friend and I were just
going to test ourselves so we so I
bought one and then it had space for 40
tests and so I thought well I might as
well just fill this whole thing up and
run 40 tests and kind of get a better
sense of how many people are positive
because at the time it was unclear of
how far spread the virus had been so so
you are really I think you might have
been the first person who did and an
amateur or professional test of how many
people had antibodies do you know
anybody tested before you know I as far
as I know I was the first report or I
did publish the first report about or on
a community kind of serum survey for
over nineteen antibodies now so you've
been sort of
paying attention his little serum
antibody thing and I know there was a
there was a article in The Wall Street
Journal that said they had some small 39
people or something and how did that go
so yeah we positive on this
convalescence Europe I mean the idea of
taking blood from somebody who's been
infected and recovered and putting their
antibodies and somebody else what's the
state of that in terms of the science I
know you're surveying the field there
yeah so on Friday I believe the first
convalescent serum therapy clinical
study was published in the authors claim
it was the first in the world publish or
at least the largest and so they did
treat 39 patients like you said with
convalescence serum therapy and it was
controlled so there was a group that did
not receive that treatment and there was
a significant improvement in survival
with the group that did receive the
convalescent serum therapy there was
about twelve point eight percent death
rate for the convalescent serum therapy
group but it was twenty four point four
percent for those who didn't receive it
so that means that the serum therapy cut
the death rate in half and that was for
people who were pretty close to death to
begin with and I think I saw in the
article that they they just assumed it
would work better if he had it earlier
but hasn't been tested I guess now is
there any reason to think that any of
this would ever be dangerous does it it
doesn't go through it wouldn't have to
go I know this is sort of outside your
area but I don't think this would have
to go through whole FDA with it the
whole FDA approval because it's their
antibodies is something we know well
enough that we don't need to go through
the whole tastic well well it is
actually FDA approved now at least with
an emergency use authorization so that
was one of the first things that became
approved as a treatment for carbon 19
because it is generally safe there's a
couple of different things
people generally test for like blood
typing you want to match the donor and
recipient and then Rh factors but other
than that it appears to be safe
so if well what would happen if you
didn't match wouldn't hurt you or would
it just not help you
suppose you had the wrong blood type
match yeah it could it could definitely
hurt you down the road I'm not you know
it has been done without blood type
matching in fact when it was first used
or the reports I've seen when it was
first users from the early 1900's and
they were not doing blood type
matching at that time but all those
reports showed significant improvement
well well if you had to guess based on
you know isn't there there are two other
cases where they've used this
convalescent blood serum approach right
was it HIV was one well I don't think it
was used or I'm not aware of it being
used for HIV but the treatment for HIV
is monoclonal antibodies and same with
Ebola and so it's similar in a way
because convalescent serum therapy is
used basically using antibodies it's
more of a kind of gross product of
antibodies where you're just taking
everything under the Sun that's in
somebody's serum and giving it to
somebody else and you're not selecting
for one specific antibody but it has
been used in SARS there is actually a
guy who got the 1901 Nobel Prize for the
development of Serapis in he solved
diphtheria epidemic in Germany in the
1890s by using serum therapies and
that's kind of where it started and so
he's the pioneer in the field
his name's Emil von Behring oh do you do
you know
what it would take to scale this up like
let's say that in a few weeks we said
yes this is the thing we need more of
this given that you have to actually
take it from people unless you're using
machines to clone it I guess how quickly
can I know you did some calculations on
how quickly you could scale up well what
what would you guess I know this is an
unfair question off the top of your head
but let's say if we were to say start
today and said all right we want to get
everybody kind of lesson blood serum
therapy like how close are we to being
able to do that is that something that
scales up very well um I think that is
generally reserved for the people that
are in poor condition you know in the
hospital so not everybody is gonna need
it but for those people it would be
possible I is obviously gonna be
dependent on your area New York got hit
so hard that I don't know if they would
have been able to keep up with demand
but generally speaking you have about 5%
of cases who end up in the ICU and those
are the people that would be candidates
to receive the therapy would they really
because why wouldn't you give it to
people even before they have it so that
they if they did get it they could
handle it more easily just because of
scalability it is tough you need to do
on plasmapheresis to get the plasma from
donors you also have to be checking
people ahead of time to make sure that
they actually had an antibody response
against the virus let me ask you some
sort of detailed questions if you're
gonna draw blood from one person and
turn that one person's blood into
antibodies how long with the whole
process take from putting the needle in
to draw the blood to to having it in
your hand and ready to give somebody
else I think that you can do quest my
paresis in a couple of hours it depends
on obviously how much you're trying to
harvest the amount that the FDA allows I
believe for
a donation is a liter per week or two
liters every two weeks and then in the
study that you're taught you were
talking about they used about 500
milliliters which is a half a liter per
patient so it looks like I don't lift it
you don't need go ahead it did to
simplify that each donor giving one
donation could handle how many people
for it looks like if over a 2-week
donation period or two Huffer one one
donation if i donate blood once how many
people would that handle to say oh
that's good
that's kind of hard to scale isn't it
yes exactly and so that's why I say it
should be reserved for only the people
that are in poor condition or in the
hospital now if you looked into the I
don't understand the the differences or
the nuances of monoclonal where you're
just taking you know the best antibodies
you can get from one real person and
then you're cloning it with machines to
scale it up it is is there a limit to
how quickly you can do that if you just
keep building machines you couldn't
could we do a ventilator type thing or
we just say all right everybody's
building monoclonal devices if you
looked into those do you know yeah so
that they're not yeah those are the
first therapies that will come online
for carbon 19 is that monoclonal
antibody therapies it takes a little bit
of time to develop because of the
process you build what are called
hybridomas and that's a fusion between a
cancer cell and an antibody creating
cell and the cancer cell makes it
immortal and then the antibody secreting
cell is fused and it starts just
producing antibodies and mass and then
you can create a ton of those cells
they're all identical and make a bunch
of antibodies in a bioreactor
and that's being done now it just takes
a little bit of time to identify the
specific antibody secreting cell
you want to use that's making good
antibodies now what once you've
identified the antibodies isn't it just
a question of making more of those
machines and more of those facilities
couldn't couldn't you just keep scaling
it up and definitely correct yeah you
could especially if you know you
somebody identified a good antibody
secreting cell and then made the
hybridomas and if they were to share
those with other people and kind of
decentralize the production and make it
scale faster that would maybe be a good
way to do it there's also you know you
should be probably combining a lot of
different hybridomas to get good
coverage for your antibodies make sure
that they're there's a good protection
there do you have you heard I haven't
seen any news coverage of the monoclonal
anything didn't do you know if anybody's
getting any traction actually doing that
I haven't seen anything that's become
available yet with those I've seen some
anecdotal reports about strong
protection there I think last week
there's a report from a company that
said they had a good candidate but you
know it's still a little early and the
other thing is that there's a difference
between having an antibody that you can
see recognizes Kovan 19 and then also
whether that antibody neutralizes the
virus so I've actually seen some
evidence in my hands where somebody can
test positive for antibodies that
recognize the virus but those antibodies
don't necessarily neutralize the virus
and then conversely somebody could have
a low level of antibodies that you know
recognize the virus but those antibodies
are very strong at neutralizing so there
is no off there so and do we have any
more visibility on how long antibodies
would last let's say you got them either
naturally by having it recovering or you
got it from
from the plasma from somebody else do
you know Israeli difference and how long
they would last you know that that's a
good question I don't you might expect
there to be a shorter window for donor
antibodies because they might have start
to get marked as non-self by your immune
system and then kind of removed but it's
a tough thing to study because you know
you start to get this mix of potentially
like antibodies made by yourself and
antibodies from the the donor and how do
you differentiate which one came from
which but I think generally like two
years is what a lot of people say if you
look at data from the original SARS
patients two years of protection is what
people are getting at least so I'm at
least some got protection out to
seventeen years so now would what do you
say that it comes down to literally just
how fast we can make this stuff I mean
that's really the gating factor right
because at this point we kind of know
it's safe and we kind of know it works
or all common sense says it works right
I mean it would be hard to imagine it
doesn't work yeah yeah it definitely
works and one of the limitations is just
getting access to the people who are
producing those antibodies so that then
you can kind of identify those antibody
secreting cells and scale this so I
would encourage anybody that's ever had
it and recovered to look into getting
tested for antibodies and look into
donating their serum for a convalescence
serum therapy because every you could
donate every week or every couple weeks
and that serum can be banked for the
future where maybe in the fall we have a
second wave or something so I think we
should be stockpiling serum now I'm in
anticipation for the fall and winter
kinda interesting so there's there's
I'd never heard before which is we have
all these strategic stockpiles of
everything from oil to PPE and
ventilators it would make perfect sense
stuff a national stack the stockpile
temporarily I don't know how long you
can store this stuff but it would that
makes perfect sense of a national
stockpile of convalescence Europe that's
actually a great idea I hope somebody's
watching this we can do something about
that yeah yeah good yeah and that like I
said requires people who have had it to
get tested for the antibodies and be
kind of active participants I think that
a lot of people are looking for
something that they can do to help
nowadays and that's one pretty easy way
to do it and you know I I think that
those people should get paid to donate
their serum a lot of them have probably
accrued pretty significant hospital
bills along the way and this would be a
way to offset those bills for them and
oh yeah oh now you now you're this is
interesting so you're talking about how
this might be a money-making thing are
you aware of anybody who's ever charged
for their antibodies for any kind of
situation does that ever happen I'm not
aware of a specific instance where
somebody's donated their antibodies
because they just had greatest
antibodies out there but you know
there's plasma donation centers all
across the country I don't know the name
of one offhand but I know there's
national chains of plasma donation
centers and they pay people the this is
very interesting because you know I I
think that the patriotic mood in the
country at the moment is so high that
you could get all the all the blood you
wanted but basically if the if the
President of the United States said
here's the deal if you've tested
positive I need you to do this go in and
offer your blood we're gonna try to see
how much where you get I believe that
patriotism alone would give you all the
blood you wanted but if you really
wanted to take it to the next level
people are people and if you could offer
more money to let's say go in
in time or the third or fourth time as
you're suggesting I would imagine that a
monetary incentive would probably have a
gigantic yes yeah yeah and I I've talked
to some people about you know the
monetary incentive and people get a
little bit uneasy sometimes about that
but my perspective is that you know it's
going to be administered in the hospital
and is the hospital making money yeah so
why shouldn't I don't yeah exactly
now so we've got safety it's really just
a production problem it seems to me and
it's almost like gosh it feels like this
is such a big deal you know every the
the biggest deal of course is wearing
masks but I would think that the second
most promising thing you know if we have
to wait for vaccines for months and
months but the things that we can do now
the second most promising thing is
probably this what do you say yeah in
terms of things that we know that work
and not having to wait around for
something that you know may never
actually happen right we there's no
guarantee that we'll have a vaccine or
anything like that
but we know this works and so you know
why not embrace it well we also pursue
other avenues to solve the problem so
that is yeah good I was just going to
point out so I started a company that
we're going to be doing antibody testing
as well and I'm specifically doing a
neutralization tests which means we're
not just testing for the presence of
antibody we're testing to see whether
your antibodies neutralize the virus and
we plan to take that data and kind of
publish it on publish the de-identified
data on open source dashboards for
anybody to check out just so everybody
can get a general sense of where their
community is in terms of relative
protection and then I plan on creating
an avenue for people who test positive
for neutralizing antibodies to be sent
information
on how to donate their plasma right so
we'll be identifying those candidates
and so then they should be told you know
here's what you can do if you're
interested in helping other people with
your unique situation or unique set of
antibodies so I've been watching the
comments and I just I just want to call
out something that I always talked about
winning attitudes and losing attitudes
and I'm watching a lot of losing
attitudes in the in the comments
specific specifically people who don't
quite appreciate and I'm gonna make them
appreciate it now the power of your
talent stack because people are sort of
saying oh data analyst what's that got
to do with this but the whole point is
that you knew how to draw blood you know
how to get these tests you've got what
do you say your background was a
biological what by bioscience yeah so
he's in a bioscience background so it
basically compiled a whole bunch of
skills together including starting a new
business initiative to try to help with
the coronavirus so what do you see
Ian jumping in and I was watching this
from the beginning and on day one
Ian was saying alright I have this at a
talents how can I help in this
coronavirus thing and then I've been
watching as you've you've you've grabbed
you know like one piece of one piece of
it at a time and tried to assemble it
into something that would be bigger than
the parts and I've been I've been
completely impressed not only at the
early data visualization stuff you're
doing because initially you were doing
data visualization some of the best ones
I've seen on the internet and then you
found that your talent stack gave you
all the way to here and actually you
know there you know it could be a you
know one of the pivotal at least
informational parts of what would be the
second most important thing we do after
masks so I'm very impressed at why
you've done and for those who are we
don't have the winning mindset what the
hell did you guys do let me just say
that while you're out in the line to you
limit to your tricks because because you
know there's always going to be somebody
on the air blah blah I hear this all
you know hey you're a cartoonist why you
do this little lot but all of those
people you're not very successful I'll
bet because if you're worried about
staying in your lane and you're worried
that people only have one Talent Ian's
got more than one Talent sorry if you
only have one Talent maybe you don't
understand how that works but if you put
enough talents together you have a
superpower and I think this is a perfect
example of it so Ian thank you for being
a a patriot and I mean that seriously
because in in times of crisis not
everybody runs toward the fire and you
did you know on day one you were running
toward the emergency you know what can I
do and we need more of you and less of
the people who were picking I I really
appreciate that Scott and I just want to
point out before I go that I can't do it
all by myself
I have a lot of help from Mikkel Staten
and Brianna Knight
they've been helping me get cure hub
going and you know it everything's you
know about being on a team and winning
team and you're we're all in this
together and no one person can make
anything work and I think it's you gotta
treat life like a positive sum game and
then you'll start to find some yes all
over the place well that's something
that's America in a in a nutshell right
there so thank you so much do you want
to name a URL that you want people look
at yeah you can go to cure - hub calm
and we have a system in place where you
can sign up and get reserve your spot in
line to get antibody test it and then
you don't pay anything but you'll get on
our mailing list and then as soon as we
have the antibody tests approved which
should be a couple weeks then we'll let
you know and then you can join the study
and you know donate a sample to get
tested we'll test you and yeah that's
all right so thank you thank you again
thanks for being a great guest
I'm gonna go on with the rest of my
program and I'll catch up with you can I
do one thing I miss the simultaneous sip
can I get another one live I gotta do it
all right I will give you the the first
ever second simultaneous sip and all you
need is a cup Ramona glass tank any kind
you ready cheers Cheers
the second simultaneous sip even better
than first all right thanks again thank
you bye
all right so you know I as much as that
the topic is interesting because in my
opinion is probably the most important
topic besides masks but I also wanted
you to get get a feel for Ian you know
just just to feel for what you are
fellow citizens if you're American and
I'm sure it's happening in every country
around the world people are just jumping
into the breach any people are running
toward this thing like crazy you know
when this is over when this is over
you're gonna be really proud that you
were a human because humans are pretty
awesome and and and humans have done
remarkable things in the past several
months and there's a lot more to come so
you know we're all lost in the details
and just trying to get through life and
you make it to the next time you can buy
groceries and I know that that's got to
be the focus but when this is done when
this is done there gonna be some real
real things to be proud about all right
let's talk about some other things I got
a suggestion on the locals platform
where I've moved a lot of my non Dilbert
stuff from Anholt
I don't know that's one name and Nolt
and alt anyway I don't know his real
name but he started referring to people
who watched CNN and MSNBC as the poorly
educated
how much do you love that so I'm gonna I
gonna adopt that that concept so instead
of what I'd be what I used to be saying
was you know it's two movies on one
screen and some people are siloed in
their in their news and they don't see
the news from the other side and I used
to sort of describe it as you know in
engineering terms but I thought this is
so much more powerful just say it oh you
only watch these networks
well you're among the poorly educated
because it's literally jus literally
poorly educated which i think is
hilarious cuz you know how much they can
hate that so apparently in the in the
polls including a Fox News poll Biden is
ahead of Trump by way more than even
Hillary was ahead of Trump at the same
time so apparently Biden is doing great
by staying at a public and just gaffing
himself and decompressing at his basis
now I don't know what could be more
ridiculous or more funny than the fact
that Joe Biden is his basement you
literally just you know decomposing and
he and he sees what great honestly are
you ever just a home and he just are
laughing about the whole Joe Biden in
the basement situation because you know
the the Biden and the basement things
sort of crept up on us right like it was
like hey I think there's this virus and
move on all right
yeah and yet in like it looks like it
might be coming this way all right and
maybe we should you know stay away from
public a little bit and next thing you
know a major candidate for president is
living in his basement and babbling
nonsense and be and because we sort of
got there gradually we've sort of
accepted it
go on are you are you sure uh-huh
can you tell me that you've never just
you just sit there by yourself and
suddenly you just sort of realise the
situation we're in would Joe Biden
decomposing in his basement and leading
leading in the polls to be the next
president of the United States I don't
have his fingers on the nuclear on the
nuclear button if that's not funny to
you it is but here's the thing that's
funniest I'm not positive so you know
you can't you know don't hold me to this
later
I'm not positive but I think I just
think we might be witnessing the
greatest practical joke of all talk and
what I mean by the greatest practical
joke is I think I can't prove this
I think conservatives are massively
lying to pollsters because it's funny
right dude
tell me I'm wrong don't you don't you
sort of suspect because if you were
saying to yourself okay I get that
president Trump's not popular and you
know all the Democrats are gonna vote
for whoever the Democrat is yeah I get
that you know that's gonna explain most
of what you see right but the the fact
that Biden's down there decomposing and
leading the polls strongly suggests it
strongly suggests that what we're seeing
is a really large national scale
practical joke because if the if the
polls still say Biden by eight points
and then Trump wins by eight points it's
going to be the greatest troll of all
time honestly it will be it will be the
most epic practical joke ever played in
the history of practical jokes and I
think that's what's happening am I wrong
get am i completely off-base because I'm
seeing a lot of people in the comments
were saying I think you're right I think
you're right I think the Republicans are
just lying to the pollsters because it's
funny speaking of funny pranks Alyssa
Milano got photographed wearing a
crochet mask and you can imagine how the
internet reacted to her crochet mask
they of course said hey there are holes
in your crochet therefore you fool you
idiot you dumb Democrat you bite in
supporting fool you fool how could you
wear a crochet map mask and worse yet if
you're gonna wear a crochet mask don't
get your photograph taken if you're
famous
and so of course Twitter went on fire
it's like doesn't know anything you
idiot your crochet bass and then Alyssa
Milano waited wait hold hold hold and
then it was ylim Alyssa Milano tweets to
one of her critics carbon filter inside
love
it was a trap it was a trap do you think
she knew that people were gonna get out
or about her crochet mask which she says
and you know I think it's probably true
she says as a carbon filter on the
inside it probably does probably does
because if you've got those good n95
masks they're the ugliest of the masks
so if she figured out a way to put a you
know a more pleasant cover over the
ugliest mask which is also the best kind
of mask maybe maybe I don't know if it
was an n95 but she said a carbon filter
so maybe that's good - all right if
you're not watching I've said this a
million times but if you're not
following Mike's or a on Twitter
you're missing one of the best shows
it's like it's like a TV show that just
goes on all the time it doesn't have a
beginning or an end like every time
every time I get on Twitter I don't see
like five certain if it's quotes and
everyone does it makes you stop and go
huh but this one if you want to
understand how to operate on the next
level this this tweet from sorry
this made me laugh for two days if this
is the whole tweet he goes
self-confidence triggers mediocre man
now of course the beauty of it is you
can't complain about without being
labeled the mediocre man so it's like
this perfect little trap it's like I
want to complain about that because I'm
really mad about your self-confidence
I'm like sort of but if I do
complain about it
does that make me a mediocre man so yeah
watching sort of itch build these little
Twitter traps for a mediocre man that's
one of the funniest things I've seen on
the Internet
telehealth has taken off I said this
before but there's even more signs of it
have you seen all the commercials
telehealth is basically just huge now we
thought that might happen but apparently
it is happening the the last thing
benefit we're gonna get from telehealth
it's gonna be gigantic and the ability
to you know practice across state lines
which i think will become permanent
would be huge and again thank you to all
of you who helped make that happen so
that's just checking in on that because
it's such a big topic and it's go in the
right direction so it's always good to
hear some good news all right what else
we got going here there's some kind of
drug called ivermectin that's getting
some good reviews and I guess it it can
interact with other medications and has
some side effects and stuff but there
were some initial trials that you know
sort of look good so I've heard nekton
there's another one I think that in the
next over the next few weeks you just
gonna hear one therapeutic after another
and it's just gonna be all positive news
now if you've done the math I did this
last night in periscope I was talking
about all the things which have cut the
wrists down so masks are supposed to be
75 percent effective distance of course
is completely effective maybe vitamin D
maybe summer will make a difference in
the warm weather you know maybe what
we've learned about nursing homes and
how to protect them maybe what we've
learned about ventilator use not to kill
people with ventilators if you if you
take each each of these many pieces of
good news each of them individually
reduces risk by some percentage from 75%
with masks down to maybe vitamin D makes
a difference or maybe it's just
correlation we don't know if it's
causation yet but maybe
hydroxychloroquine and zinc if you get a
Merlin he's 20% benefit maybe there's
some people we can get with this
convalescent blood serum so we now have
off the top of my head maybe 10 to 12
different things we've either developed
as
tool or learned which also allows us to
reduce risk I feel like we have all the
tools to within a few weeks we're gonna
have the risk down to it's gonna
approach to zero I mean it's almost
gonna disappear I think monoclonal
antibody is almost ready somebody says
yeah and that could be huge the
monoclonal antibodies just could be huge
all right and then somebody says primer
primarily immune system strength let me
ask you this I want to see this in the
comments when when this whole thing
started I was advising everybody to just
make sure they took care of their immune
system so in other words you know get
out get a little light exercise get some
Sun get some sleepy right you know all
the usual things how many of you have
done that how many of you in the
comments it'll take a little time like
here but in the comments tell me if you
feel that you've done something that
would boost your immune system have you
have you intentionally boosted your
immune system with all the yeses Wow
almost every person every so far every
person who's answering you saying yes
think about that well what kind of what
kind of change does that make in your
life and in civilization if suddenly 370
million people just decided to get
serious about boosting their immunity
and their health oh my god I am so
impressed uh for those of you who are
listening to this it is a non broken
string of yeses I've never seen so much
agreement somebody lost 20 pounds
bicycle riding outdoors yes definitely
yes yes yes yes immune system way up yes
oh my goodness I am so so impressed very
impressed I've never seen anything like
this are you as impressed as I am take
take a look at these
comments coming by they're still
absolutely solidly yes holy cow this is
one of the this is the most
underreported story of the year isn't it
wouldn't you say this is the most
underreported story if if we had not had
a corona virus and suddenly you found
that 370 million Americans and I'm
guessing other countries doing something
similar if you found that you know
hundreds of millions of people suddenly
took seriously their health what did we
just do to the entire health care cost
of this country how much of this is
going to become habit you know I'm
wondering if you think that you'll be
able to turn this into habit the trouble
is you know a lot of us not going to
work in the normal ways we don't have
the normal schedule so it's gonna be
harder when you're trying to work it in
with your normal schedule but wow I am
so impressed with all of you genuinely
somebody stopped smoking congratulations
congratulations on stopping smoking that
is hard alright so well that might be
the good news for this may be our
healthcare cost just took 20% hit simply
because we're we're in better shape and
we know how to do this so where can you
outdoors shoot I don't understand that
question
all right well I'm impressed with you
all and I'm gonna leave you on that note
hope you learned something today and
I'll talk to you tonight