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Episodes › Episode #994

Episode 994 Scott Adams - Convalescent Blood Plasma, Biden, Golf, and Scarborough

Episode #994 May 24, 2020 47:03 12,304 views

My new book LOSERTHINK, available now on Amazon https://tinyurl.com/rqmjc2a Content: President Trump, Joe Scarborough and an intern Special Guest: Ian Hilgart-Martiszus @IanFelipeSays Convalescent Blood (Plasma) Therapy cure-hub.com for antibody testing Gaffing and decomposing in your basement is gold for poll numbers Alyssa Milano's crochet mask...it was a trap! ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ If you would like to enjoy this same content plus bonus content from Scott Adams, including micro-lessons on lots of useful topics to build your talent stack, please see scottadams.locals.com for full access to that secret treasure.

Opening General Commentary

Um, did you wonder where I was? I'm two minutes late. I couldn't get my Wi-Fi working. A little power outage last night screwed things up, but I'm good now. We're back, and that means it's time for a little thing you call the simultaneous sip. I call it that too.

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SimultaneousSip General Commentary

And all it takes is a cup of mud or a glass of tankard or any kind of vessel that can hold your favorite liquid. I like coffee. And join me now for the unparalleled pleasure, the dopamine hit at the end of the day, the thing that makes everything better, including the damn pandemic. It's called the…

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NewsReaction Politics as Persuasion

Now if you joined us last night I had a little technical difficulty. I was trying to bring on a special guest to talk about convalescent blood serum, and as soon as he's ready we're going to try that again this morning. So I'll wait till I see when Ian gets on. All right, let's tell him we're good n…

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MainContent Health & Biohacking

All right, let's see if we get Ian on the line. This will be a test of the technology. I think we got it. I think we got it. Oh, seriously? Because I know we had a Wi-Fi problem yesterday and it looks like we got a Wi-Fi problem today. Well whatever the problem is, it doesn't look like that's going…

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MainContent Talent Stack

So I've been watching the comments and I just want to call out something that I always talked about: winning attitudes and losing attitudes. And I'm watching a lot of losing attitudes in the comments, specifically people who don't quite appreciate, and I'm going to make them appreciate it now, the p…

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SimultaneousSip General Commentary

All right so thank you. Thank you again. Thanks for being a great guest. I'm going to go on with the rest of my program and I'll catch up with you. Can I do one thing? I missed the simultaneous sip. Can I get another one live? I gotta do it. All right I will give you the first ever second simultaneo…

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MainContent The Golden Age

All right so you know as much as the topic is interesting because in my opinion it's probably the most important topic besides masks, but I also wanted you to get a feel for Ian. You know just a feel for what your fellow citizens, if you're American, and I'm sure it's happening in every country arou…

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NewsReaction Media & Fake News

All right let's talk about some other things. I got a suggestion on the Locals platform where I've moved a lot of my non-Dilbert stuff. From Anholt, I don't know that's one name, and Nolt and Alt anyway I don't know his real name but he started referring to people who watched CNN and MSNBC as the po…

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MainContent Health & Biohacking

Now if you've done the math, I did this last night in Periscope, I was talking about all the things which have cut the risk down. So masks are supposed to be 75 percent effective. Distance of course is completely effective. Maybe vitamin D. Maybe summer will make a difference in the warm weather. Ma…

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Closing Health & Biohacking

All right well I'm impressed with you all and I'm going to leave you on that note. Hope you learned something today and I'll talk to you tonight.

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Um, did you wonder where I was? I'm two minutes late. I couldn't get my Wi-Fi working. A little power outage last night screwed things up, but I'm good now. We're back, and that means it's time for a little thing you call the simultaneous sip. I call it that too. And all it takes is a cup of mud or a glass of tankard or any kind of vessel that can hold your favorite liquid. I like coffee. And join me now for the unparalleled pleasure, the dopamine hit at the end of the day, the thing that makes everything better, including the damn pandemic. It's called the simultaneous sip, and it happens now.

Go. Mmm.

Now if you joined us last night I had a little technical difficulty. I was trying to bring on a special guest to talk about convalescent blood serum, and as soon as he's ready we're going to try that again this morning. So I'll wait till I see when Ian gets on. All right, let's tell him we're good now.

In the news, my favorite story is that President Trump apparently wanted to go golfing this weekend but he didn't want it to be the biggest story. So what do you do if you want to go golfing and you're the president and you don't want it to be the biggest story for three days? Well, on the way out the door to golf, what you do is you send a tweet that accuses Joe Scarborough of murder. You have to appreciate how much fun that is. Now of course not for the family of the victim who died many years ago, but the fact that Trump would accuse somebody of murder before he goes golfing is beautiful.

So I see Ian has joined. So let me just finish the story a little. Adam, on. Here's my take on that. Now on one hand it's completely outrageous and inappropriate that the President of the United States would accuse Joe Scarborough of murder when there's no indication that he actually murdered anybody. There was some young woman who hit her head and died in his office years ago. Now that's all we know, and she had some health problem that suggests that she just passed out. But the fact that the president would say that, now you say to yourself, well that's all wrong. That is so wrong. That is wrong on a level that's deeper than any wrongness, except we are talking about Joe Scarborough, who did lie about the president in the worst possible way for years.

I believe he accused the president of suggesting people should drink bleach. That never happened. I think he suggested the president had called neo-Nazis in Charlottesville fine people. That never happened. So is it fundamentally different to accuse somebody of being pro-Nazi versus saying you murdered your girlfriend? They're not that different, really, because once you have accepted that you can say absolutely anything in the political context, there's just no penalty. You can say absolutely anything. The president just took the rules and said, what are the rules? The rules are you can say anything, really just anything. I can just make up anything and I can just say it in public and it's a headline. All right, how about Joe Scarborough's a murderer? We'll see how that goes. Went pretty well.

All right, let's see if we get Ian on the line. This will be a test of the technology. I think we got it. I think we got it. Oh, seriously? Because I know we had a Wi-Fi problem yesterday and it looks like we got a Wi-Fi problem today. Well whatever the problem is, it doesn't look like that's going to get solved. I'll try it one more time but then I think we should maybe give up on this if it doesn't work this time. Yeah, and we'll try you one more time. Yeah, hey, let's make this work. This is the first time the technology has worked more than five seconds, so I feel good about it. That's a good sign. All right, good strong signal.

All right, Ian, first of all let me see if I can pronounce your name correctly. Ian Hillgard Martius? Pretty close, yes. You nailed it. All right. Can you tell the audience what your background is and how that relates specifically to the convalescent blood plasma testing situation? Give them a little background on you.

Okay, so my background is that I worked in bioscience for about ten years and then I ended up kind of leaving academic bioscience and taught myself to program and became a data analyst and started working for a corporation as a data analyst. And when the COVID stuff started to hit I would figure out ways to harvest public data to do public data analysis that I could publish so to help people understand the situation a little better. And then through that process I started to think about different answers that I thought we needed that maybe we weren't getting from the media. And one of the things I thought about was, well what can we do now? What can we do before there's a vaccine? Because there's going to be people who can't wait that long and the development of new therapeutics takes so long that a lot of people would end up dying while they wait. And so we got to figure something out in the middle.

So tell us what you did, because I was sort of following along early on and you put together your own tests, right?

Well it wasn't necessarily my own test. I bought a commercially available test kit. I just happened to become aware of its existence pretty early. I suppose the way that I became aware of it is that I just got like a spam email because when you buy something from a vendor they put you on a mailing list and then they always blast out these kind of spam advertisements. And so I got one of those that said, oh hey we have these COVID-19 antibody tests. And so I thought, oh I want to buy one of those. And my friend and I were just going to test ourselves. So I bought one and then it had space for 40 tests and so I thought, well I might as well just fill this whole thing up and run 40 tests and kind of get a better sense of how many people are positive because at the time it was unclear how far spread the virus had been.

So you are really, I think you might have been the first person who did an amateur or professional test of how many people had antibodies. Do you know if anybody tested before you?

No, as far as I know I was the first to report or I did publish the first report on a community kind of serum survey for COVID-19 antibodies.

Now you've been sort of paying attention to this little serum antibody thing and I know there was an article in The Wall Street Journal that said they had some small study, 39 people or something. And how did that go?

So yeah, we posted on this convalescent serum. I mean the idea of taking blood from somebody who's been infected and recovered and putting their antibodies in somebody else, what's the state of that in terms of the science? I know you're surveying the field there.

Yeah, so on Friday I believe the first convalescent serum therapy clinical study was published and the authors claim it was the first in the world published, or at least the largest. And so they did treat 39 patients like you said with convalescent serum therapy and it was controlled. So there was a group that did not receive that treatment and there was a significant improvement in survival with the group that did receive the convalescent serum therapy. There was about a 12.8 percent death rate for the convalescent serum therapy group but it was 24.4 percent for those who didn't receive it. So that means that the serum therapy cut the death rate in half and that was for people who were pretty close to death to begin with.

And I think I saw in the article that they just assumed it would work better if you had it earlier but it hasn't been tested. I guess now is there any reason to think that any of this would ever be dangerous? It doesn't go through, it wouldn't have to go, I know this is sort of outside your area, but I don't think this would have to go through the whole FDA approval because it's their antibodies. It's something we know well enough that we don't need to go through the whole thing, right?

Well it is actually FDA approved now, at least with an emergency use authorization. So that was one of the first things that became approved as a treatment for COVID-19 because it is generally safe. There's a couple of different things people generally test for like blood typing. You want to match the donor and recipient and then Rh factors. But other than that it appears to be safe.

So what would happen if you didn't match? Would it hurt you or would it just not help you? Suppose you had the wrong blood type match.

Yeah it could definitely hurt you down the road. It has been done without blood type matching. In fact when it was first used, the reports I've seen when it was first used are from the early 1900s and they were not doing blood type matching at that time but all those reports showed significant improvement.

Well if you had to guess based on, you know, isn't there two other cases where they've used this convalescent blood serum approach? Right, was it HIV was one?

Well I don't think it was used, or I'm not aware of it being used for HIV, but the treatment for HIV is monoclonal antibodies and same with Ebola. And so it's similar in a way because convalescent serum therapy is basically using antibodies. It's more of a kind of gross product of antibodies where you're just taking everything under the sun that's in somebody's serum and giving it to somebody else and you're not selecting for one specific antibody. But it has been used in SARS. There is actually a guy who got the 1901 Nobel Prize for the development of serum therapy. He solved a diphtheria epidemic in Germany in the 1890s by using serum therapies and that's kind of where it started. And so he's the pioneer in the field. His name's Emil von Behring.

Do you know what it would take to scale this up? Like let's say that in a few weeks we said yes this is the thing, we need more of this. Given that you have to actually take it from people unless you're using machines to clone it I guess, how quickly can, I know you did some calculations on how quickly you could scale up. What would you guess? I know this is an unfair question off the top of your head but let's say if we were to start today and say all right we want to get everybody convalescent blood serum therapy, like how close are we to being able to do that? Is that something that scales up very well?

I think that is generally reserved for the people that are in poor condition, in the hospital. So not everybody is going to need it but for those people it would be possible. It's obviously going to be dependent on your area. New York got hit so hard that I don't know if they would have been able to keep up with demand. But generally speaking you have about 5% of cases who end up in the ICU and those are the people that would be candidates to receive the therapy.

Would they really? Because why wouldn't you give it to people even before they have it so that if they did get it they could handle it more easily? Just because of scalability it is tough. You need to do plasmapheresis to get the plasma from donors. You also have to be checking people ahead of time to make sure that they actually had an antibody response against the virus.

Let me ask you some sort of detailed questions. If you're going to draw blood from one person and turn that one person's blood into antibodies, how long would the whole process take from putting the needle in to draw the blood to having it in your hand and ready to give somebody else?

I think that you can do plasmapheresis in a couple of hours. It depends obviously how much you're trying to harvest. The amount that the FDA allows I believe for a donation is a liter per week or two liters every two weeks. And then in the study that you were talking about they used about 500 milliliters which is a half a liter per patient. So it looks like if one donor giving one donation, over a two-week donation period, could handle two people.

One donation. If I donate blood once, how many people would that handle? So that's good. That's kind of hard to scale, isn't it?

Yes exactly. And so that's why I say it should be reserved for only the people that are in poor condition or in the hospital.

Now if you looked into the, I don't understand the differences or the nuances of monoclonal where you're just taking the best antibodies you can get from one real person and then you're cloning it with machines to scale it up. Is there a limit to how quickly you can do that if you just keep building machines? Couldn't we do a ventilator type thing where we just say all right everybody's building monoclonal devices? If you looked into those, do you know?

So they're not. Those are the first therapies that will come online for COVID-19 is monoclonal antibody therapies. It takes a little bit of time to develop because of the process. You build what are called hybridomas and that's a fusion between a cancer cell and an antibody creating cell and the cancer cell makes it immortal and then the antibody secreting cell is fused and it starts just producing antibodies en masse. And then you can create a ton of those cells. They're all identical and make a bunch of antibodies in a bioreactor and that's being done now. It just takes a little bit of time to identify the specific antibody secreting cell you want to use that's making good antibodies.

Now once you've identified the antibodies isn't it just a question of making more of those machines and more of those facilities? Couldn't you just keep scaling it up?

Definitely, correct. Yeah you could, especially if somebody identified a good antibody secreting cell and then made the hybridomas and if they were to share those with other people and kind of decentralize the production and make it scale faster that would maybe be a good way to do it. There's also, you should be probably combining a lot of different hybridomas to get good coverage for your antibodies, make sure that there's good protection there.

Have you heard, I haven't seen any news coverage of the monoclonal. Do you know if anybody's getting any traction actually doing that?

I haven't seen anything that's become available yet with those. I've seen some anecdotal reports about strong protection there. I think last week there was a report from a company that said they had a good candidate but it's still a little early. And the other thing is that there's a difference between having an antibody that you can see recognizes COVID-19 and then also whether that antibody neutralizes the virus. So I've actually seen some evidence in my hands where somebody can test positive for antibodies that recognize the virus but those antibodies don't necessarily neutralize the virus. And then conversely somebody could have a low level of antibodies that recognize the virus but those antibodies are very strong at neutralizing. So there is nuance there.

And do we have any more visibility on how long antibodies would last? Let's say you got them either naturally by having it and recovering or you got it from the plasma from somebody else. Do you know? Is there a difference in how long they would last?

That's a good question. I don't. You might expect there to be a shorter window for donor antibodies because they might start to get marked as non-self by your immune system and then kind of removed. But it's a tough thing to study because you start to get this mix of potentially antibodies made by yourself and antibodies from the donor and how do you differentiate which one came from which? But I think generally like two years is what a lot of people say. If you look at data from the original SARS patients, two years of protection is what people are getting at least. Some got protection out to seventeen years.

Now would you say that it comes down to literally just how fast we can make this stuff? I mean that's really the gating factor, right? Because at this point we kind of know it's safe and we kind of know it works or all common sense says it works. It would be hard to imagine it doesn't work.

Yeah it definitely works and one of the limitations is just getting access to the people who are producing those antibodies so that then you can kind of identify those antibody secreting cells and scale this. So I would encourage anybody that's ever had it and recovered to look into getting tested for antibodies and look into donating their serum for convalescent serum therapy because you could donate every week or every couple weeks and that serum can be banked for the future where maybe in the fall we have a second wave or something. So I think we should be stockpiling serum now in anticipation for the fall and winter.

Kind of interesting. So there's, I'd never heard before, which is we have all these strategic stockpiles of everything from oil to PPE and ventilators. It would make perfect sense to have a national stockpile of convalescent serum. That's actually a great idea. I hope somebody's watching this. We can do something about that.

Yeah, and that requires people who have had it to get tested for the antibodies and be kind of active participants. I think that a lot of people are looking for something that they can do to help nowadays and that's one pretty easy way to do it. And I think that those people should get paid to donate their serum. A lot of them have probably accrued pretty significant hospital bills along the way and this would be a way to offset those bills for them.

Now you're talking about how this might be a money-making thing. Are you aware of anybody who's ever charged for their antibodies for any kind of situation? Does that ever happen?

I'm not aware of a specific instance where somebody's donated their antibodies because they just had the greatest antibodies out there. But there's plasma donation centers all across the country. I don't know the name of one offhand but I know there's national chains of plasma donation centers and they pay people.

This is very interesting because the patriotic mood in the country at the moment is so high that you could get all the blood you wanted basically if the President of the United States said here's the deal, if you've tested positive I need you to go in and offer your blood. We're going to try to see how much we get. I believe that patriotism alone would give you all the blood you wanted. But if you really wanted to take it to the next level, people are people, and if you could offer more money to let's say go in a second or third or fourth time as you're suggesting, I would imagine that a monetary incentive would probably have a gigantic effect.

Yeah, and I've talked to some people about the monetary incentive and people get a little bit uneasy sometimes about that but my perspective is that it's going to be administered in the hospital and is the hospital making money? Yeah. So why shouldn't the donor?

Exactly. Now so we've got safety. It's really just a production problem it seems to me. And it's almost like gosh it feels like this is such a big deal. The biggest deal of course is wearing masks but I would think that the second most promising thing, if we have to wait for vaccines for months and months, the things that we can do now, the second most promising thing is probably this. What do you say?

In terms of things that we know that work and not having to wait around for something that may never actually happen. There's no guarantee that we'll have a vaccine or anything like that but we know this works and so why not embrace it while we also pursue other avenues to solve the problem.

I was just going to point out, so I started a company that we're going to be doing antibody testing as well and I'm specifically doing a neutralization test which means we're not just testing for the presence of antibody, we're testing to see whether your antibodies neutralize the virus. And we plan to take that data and publish the de-identified data on open source dashboards for anybody to check out just so everybody can get a general sense of where their community is in terms of relative protection. And then I plan on creating an avenue for people who test positive for neutralizing antibodies to be sent information on how to donate their plasma. So we'll be identifying those candidates and so then they should be told here's what you can do if you're interested in helping other people with your unique situation or unique set of antibodies.

So I've been watching the comments and I just want to call out something that I always talked about: winning attitudes and losing attitudes. And I'm watching a lot of losing attitudes in the comments, specifically people who don't quite appreciate, and I'm going to make them appreciate it now, the power of your talent stack. Because people are sort of saying, oh data analyst, what's that got to do with this? But the whole point is that you knew how to draw blood, you know how to get these tests, you've got what do you say your background was, a biological, bioscience. So he's got a bioscience background. So it basically compiled a whole bunch of skills together including starting a new business initiative to try to help with the coronavirus.

So what do you see? Ian jumping in and I was watching this from the beginning and on day one Ian was saying all right I have this talent stack, how can I help in this coronavirus thing? And then I've been watching as you've grabbed one piece at a time and tried to assemble it into something that would be bigger than the parts. And I've been completely impressed not only at the early data visualization stuff you're doing because initially you were doing data visualization, some of the best ones I've seen on the internet, and then you found that your talent stack gave you all the way to here and actually could be one of the pivotal at least informational parts of what would be the second most important thing we do after masks. So I'm very impressed at what you've done.

And for those of you who don't have the winning mindset, what the hell did you guys do? Let me just say that while you're out in the line to you limit to your tricks because there's always going to be somebody on the air, blah blah, I hear this all the time, hey you're a cartoonist, why are you doing this? But all of those people, you're not very successful I'll bet because if you're worried about staying in your lane and you're worried that people only have one talent, Ian's got more than one talent. Sorry if you only have one talent, maybe you don't understand how that works. But if you put enough talents together you have a superpower and I think this is a perfect example of it.

So Ian thank you for being a patriot and I mean that seriously because in times of crisis not everybody runs toward the fire and you did. On day one you were running toward the emergency. What can I do? And we need more of you and less of the people who are picking. I really appreciate that Scott and I just want to point out before I go that I can't do it all by myself. I have a lot of help from Mikkel Staten and Brianna Knight. They've been helping me get CureHub going and everything's about being on a team, a winning team, and we're all in this together and no one person can make anything work. And I think you've got to treat life like a positive sum game and then you'll start to find some wins all over the place.

Well that's something that's America in a nutshell right there. So thank you so much. Do you want to name a URL that you want people to look at?

Yeah you can go to cure-hub.com and we have a system in place where you can sign up and reserve your spot in line to get an antibody test and then you don't pay anything but you'll get on our mailing list and then as soon as we have the antibody tests approved which should be a couple weeks then we'll let you know and then you can join the study and donate a sample to get tested. We'll test you and yeah that's it.

All right so thank you. Thank you again. Thanks for being a great guest. I'm going to go on with the rest of my program and I'll catch up with you. Can I do one thing? I missed the simultaneous sip. Can I get another one live? I gotta do it. All right I will give you the first ever second simultaneous sip. And all you need is a cup, Ramona glass, tankard, any kind. You ready? Cheers. Cheers. The second simultaneous sip, even better than the first.

All right thanks again. Thank you. Bye.

All right so you know as much as the topic is interesting because in my opinion it's probably the most important topic besides masks, but I also wanted you to get a feel for Ian. You know just a feel for what your fellow citizens, if you're American, and I'm sure it's happening in every country around the world, people are just jumping into the breach and people are running toward this thing like crazy. When this is over, when this is over you're going to be really proud that you were a human because humans are pretty awesome and humans have done remarkable things in the past several months and there's a lot more to come. So we're all lost in the details and just trying to get through life and make it to the next time you can buy groceries and I know that that's got to be the focus but when this is done, when this is done there are going to be some real things to be proud about.

All right let's talk about some other things. I got a suggestion on the Locals platform where I've moved a lot of my non-Dilbert stuff. From Anholt, I don't know that's one name, and Nolt and Alt anyway I don't know his real name but he started referring to people who watched CNN and MSNBC as the poorly educated. How much do you love that? So I'm going to adopt that concept. So instead of what I used to be saying was you know it's two movies on one screen and some people are siloed in their news and they don't see the news from the other side and I used to sort of describe it in engineering terms but I thought this is so much more powerful. Just say it, oh you only watch these networks? Well you're among the poorly educated. Because it's literally just poorly educated which I think is hilarious because you know how much they can hate that.

So apparently in the polls, including a Fox News poll, Biden is ahead of Trump by way more than even Hillary was ahead of Trump at the same time. So apparently Biden is doing great by staying in his basement and just gaffing himself and decomposing at his basement. Now I don't know what could be more ridiculous or more funny than the fact that Joe Biden is in his basement. You literally just, you know, decomposing. And he stays at home and he just, are you ever just at home and you just are laughing about the whole Joe Biden in the basement situation? Because the Biden in the basement thing sort of crept up on us, right? Like it was like hey I think there's this virus and move on. All right yeah and yet it looks like it might be coming this way. All right and maybe we should stay away from public a little bit. And next thing you know a major candidate for president is living in his basement and babbling nonsense. And because we sort of got there gradually we've sort of accepted it.

Go on. Are you sure? Can you tell me that you've never just sat there by yourself and suddenly you just sort of realize the situation we're in with Joe Biden decomposing in his basement and leading in the polls to be the next president of the United States? I don't have his fingers on the nuclear button. If that's not funny to you it is. But here's the thing that's funniest. I'm not positive so don't hold me to this later. I'm not positive but I think we might be witnessing the greatest practical joke of all time. And what I mean by the greatest practical joke is I think, I can't prove this, I think conservatives are massively lying to pollsters because it's funny. Tell me I'm wrong. Don't you sort of suspect? Because if you were saying to yourself okay I get that President Trump's not popular and all the Democrats are going to vote for whoever the Democrat is, yeah I get that. That's going to explain most of what you see. But the fact that Biden's down there decomposing and leading the polls strongly suggests that what we're seeing is a really large national scale practical joke. Because if the polls still say Biden by eight points and then Trump wins by eight points it's going to be the greatest troll of all time. Honestly it will be the most epic practical joke ever played in the history of practical jokes and I think that's what's happening. Am I wrong? Am I completely off base? Because I'm seeing a lot of people in the comments who are saying I think you're right. I think the Republicans are just lying to the pollsters because it's funny.

Speaking of funny pranks, Alyssa Milano got photographed wearing a crochet mask and you can imagine how the internet reacted to her crochet mask. They of course said hey there are holes in your crochet therefore you fool, you idiot, you dumb Democrat, you Biden supporting fool. How could you wear a crochet mask? And worse yet if you're going to wear a crochet mask don't get your photograph taken if you're famous. And so of course Twitter went on fire. It's like she doesn't know anything, you idiot, your crochet mask. And then Alyssa Milano waited. Wait hold hold hold. And then it was, Alyssa Milano tweets to one of her critics, carbon filter inside. Love it. It was a trap. It was a trap. Do you think she knew that people were going to go after her crochet mask? Which she says, and I think it's probably true, she says has a carbon filter on the inside. It probably does because if you've got those good N95 masks they're the ugliest of the masks. So if she figured out a way to put a more pleasant cover over the ugliest mask which is also the best kind of mask, maybe. I don't know if it was an N95 but she said a carbon filter so maybe that's good too.

All right if you're not watching, I've said this a million times but if you're not following Mike Cernovich on Twitter you're missing one of the best shows. It's like a TV show that just goes on all the time. It doesn't have a beginning or an end. Like every time I get on Twitter I see like five Cernovich quotes and everyone does it makes you stop and go huh. But this one, if you want to understand how to operate on the next level, this tweet from Cernovich made me laugh for two days. If this is the whole tweet he goes, self-confidence triggers mediocre man. Now of course the beauty of it is you can't complain about it without being labeled the mediocre man. So it's like this perfect little trap. It's like I want to complain about that because I'm really mad about your self-confidence but if I do complain about it does that make me a mediocre man? So watching Cernovich build these little Twitter traps for the mediocre man, that's one of the funniest things I've seen on the internet.

Telehealth has taken off. I said this before but there's even more signs of it. Have you seen all the commercials? Telehealth is basically just huge now. We thought that might happen but apparently it is happening. The lasting benefit we're going to get from telehealth is going to be gigantic and the ability to practice across state lines which I think will become permanent would be huge. And again thank you to all of you who helped make that happen. So just checking in on that because it's such a big topic and it's going in the right direction so it's always good to hear some good news.

All right what else we got going here? There's some kind of drug called ivermectin that's getting some good reviews and I guess it can interact with other medications and has some side effects and stuff but there were some initial trials that sort of look good. So ivermectin. There's another one. I think that over the next few weeks you're just going to hear one therapeutic after another and it's just going to be all positive news.

Now if you've done the math, I did this last night in Periscope, I was talking about all the things which have cut the risk down. So masks are supposed to be 75 percent effective. Distance of course is completely effective. Maybe vitamin D. Maybe summer will make a difference in the warm weather. Maybe what we've learned about nursing homes and how to protect them. Maybe what we've learned about ventilator use not to kill people with ventilators. If you take each of these many pieces of good news, each of them individually reduces risk by some percentage from 75% with masks down to maybe vitamin D makes a difference or maybe it's just correlation we don't know if it's causation yet but maybe hydroxychloroquine and zinc if you get it early maybe 20% benefit. Maybe there's some people we can get with this convalescent blood serum. So we now have off the top of my head maybe 10 to 12 different things we've either developed as tools or learned which also allows us to reduce risk. I feel like we have all the tools to within a few weeks we're going to have the risk down to, it's going to approach zero. I mean it's almost going to disappear. I think monoclonal antibodies, almost ready somebody says yeah and that could be huge. The monoclonal antibodies just could be huge.

All right and then somebody says primarily immune system strength. Let me ask you this. I want to see this in the comments. When this whole thing started I was advising everybody to just make sure they took care of their immune system. So in other words get a little light exercise, get some sun, get some sleep, all the usual things. How many of you have done that? How many of you in the comments, it'll take a little time to load here but in the comments tell me if you feel that you've done something that would boost your immune system. Have you intentionally boosted your immune system? With all the yeses. Wow almost every person, every so far every person who's answering is saying yes. Think about that. What kind of change does that make in your life and in civilization if suddenly 370 million people just decided to get serious about boosting their immunity and their health? Oh my god I am so impressed.

For those of you who are listening to this it is a non-broken string of yeses. I've never seen so much agreement. Somebody lost 20 pounds bicycle riding outdoors. Yes definitely. Yes yes yes yes. Immune system way up. Yes. Oh my goodness I am so so impressed. Very impressed. I've never seen anything like this. Are you as impressed as I am? Take a look at these comments coming by. They're still absolutely solidly yes. Holy cow this is one of the, this is the most underreported story of the year isn't it? Wouldn't you say this is the most underreported story? If we had not had a coronavirus and suddenly you found that 370 million Americans and I'm guessing other countries doing something similar, if you found that hundreds of millions of people suddenly took seriously their health, what did we just do to the entire health care cost of this country? How much of this is going to become habit?

You know I'm wondering if you think that you'll be able to turn this into habit. The trouble is a lot of us not going to work in the normal ways. We don't have the normal schedule so it's going to be harder when you're trying to work it in with your normal schedule. But wow I am so impressed with all of you. Genuinely. Somebody stopped smoking. Congratulations. Congratulations on stopping smoking. That is hard.

All right so well that might be the good news for this. Maybe our healthcare cost just took a 20% hit simply because we're in better shape and we know how to do this. So where can you outdoors shoot? I don't understand that question.

All right well I'm impressed with you all and I'm going to leave you on that note. Hope you learned something today and I'll talk to you tonight.

um did you wonder where I was I'm two minutes late I couldn't get my Wi-Fi working a little power outage last night s things up but I'm good now or back and that means it's time for a little thing you call simultaneous it I call it that too and all it takes is a cup of mud or a glass of tanker gels to design a Kent injector flies got vessel of any kind hello with your favorite liquid I like coffee and join me now for the unparalleled pleasure the dopamine the end of the day the thing that makes everything better including the damn pandemic it's called the simultaneous if and it happens now go mmm now if you joined us last night I had a little technical difficulty I was trying to bring on a special guest to talk about convalescent blood serum and as soon as he's ready we're gonna try that again this morning so I'll wait to wait till see when Ian gets on all right let's tell him we're good now in the news my favorite story is that President Trump apparently wanted to go golfing this weekend Behati didn't want it to be the biggest story so what do you do if you want to go golfing and you're the president and you don't want it to be the biggest story for three days well on the way out the door to golf what you do is you to send a tweet that accuses Joe Scarborough of murder they have to appreciate how much fun that is now of course now for the family of the victim who died many years ago but the fact that Trump would accuse somebody of murder before he goes golfing is beautiful so I see Ian as joined so let me just finish the story a little Adam on now here's my take of that now on one hand it's completely outrageous and inappropriate that the President of the United States would accuse Joe Scarborough of murder when there's no indication that he actually murdered anybody there was some young woman who hit her head and died in his office years ago now that's all we know and she had some health problem that suggests that she just passed out yet but the fact that the president would say that now you say to yourself well that's all wrong that is so wrong that is wrong on a level that's deeper than any wrongness except except we are talking about Joe Scarborough who did lie about the president in the worst possible way for years I believe he accused the president of suggesting people should drink bleach that never happened I think he suggested the President had called neo-nazis in Charlottesville fine people that never happened so is it fundamentally different to accuse somebody of being pro-nazi versus saying you murdered your girlfriend they're not that different really because once you have accepted that you can say absolutely anything in the political context there's just no penalty you can say absolutely anything the president just took the rules and said what are the rules of the rules are you can say anything really just anything I can just make up anything and I can just say it public and it's a headline all right how about joe scarborough's a murderer we'll see how that goes went pretty well all right let's see if we get Jana Ian on the line this will be a test of the technology I think we got it I think we got it Oh seriously because I know we had a Wi-Fi problem yesterday and it looks like we got a Wi-Fi problem today well whatever the problem is doesn't look like that's gonna get solved I'll try it one more time but then I think we should maybe give up on this if it doesn't work this time yeah and we'll try you one more time yeah hey let's make this work the this is the first time the technology has worked more than five seconds so I feel good about it that's a good sign all right good strong signal all right Ian first of all let me see if I can pronounce your name correctly Ian Hill guard Martius pretty close yes yes you nailed it all right can you tell the audience what your background is and how that relates specifically to the convalescent blood plasma testing situation give them a little background on you okay so my background is that I worked in bioscience for about ten years and then I ended up kind of leaving academic bioscience and taught myself to program and become a data analyst and started working in corporate and for a corporation as a data analyst and when the co good stuff started to hit I would figure out ways to harvest public data to do public data analysis that I could publish so to help people understand the situation a little better and then through that process I started to you know think about different answers that I thought we needed that maybe we weren't getting from the media and one of the things I thought about as well as you know what can we do now what can we do before there's a vaccine because there's going to be people who can't wait that long and the development of new therapeutics that takes so long that a lot of people would end up dying while they wait and so you know we got to figure something out in the middle so tell us what you did because I was I was sort of following the law early on and and you put together your own tests right well it wasn't necessarily my own test I bought a commercially available test kit I just happened to become aware of its existence pretty early I suppose in the way that I became aware of it is that I just got like a spam email because you know when you buy something from a vendor they put you on a mailing list and then they always blast out these kind of spam advertisements and so I got one of those that said oh hey we have these Ovid 19 antibody tests and so I thought oh I want to buy one of those and my friend and I were just going to test ourselves so we so I bought one and then it had space for 40 tests and so I thought well I might as well just fill this whole thing up and run 40 tests and kind of get a better sense of how many people are positive because at the time it was unclear of how far spread the virus had been so so you are really I think you might have been the first person who did and an amateur or professional test of how many people had antibodies do you know anybody tested before you know I as far as I know I was the first report or I did publish the first report about or on a community kind of serum survey for over nineteen antibodies now so you've been sort of paying attention his little serum antibody thing and I know there was a there was a article in The Wall Street Journal that said they had some small 39 people or something and how did that go so yeah we positive on this convalescence Europe I mean the idea of taking blood from somebody who's been infected and recovered and putting their antibodies and somebody else what's the state of that in terms of the science I know you're surveying the field there yeah so on Friday I believe the first convalescent serum therapy clinical study was published in the authors claim it was the first in the world publish or at least the largest and so they did treat 39 patients like you said with convalescence serum therapy and it was controlled so there was a group that did not receive that treatment and there was a significant improvement in survival with the group that did receive the convalescent serum therapy there was about twelve point eight percent death rate for the convalescent serum therapy group but it was twenty four point four percent for those who didn't receive it so that means that the serum therapy cut the death rate in half and that was for people who were pretty close to death to begin with and I think I saw in the article that they they just assumed it would work better if he had it earlier but hasn't been tested I guess now is there any reason to think that any of this would ever be dangerous does it it doesn't go through it wouldn't have to go I know this is sort of outside your area but I don't think this would have to go through whole FDA with it the whole FDA approval because it's their antibodies is something we know well enough that we don't need to go through the whole tastic well well it is actually FDA approved now at least with an emergency use authorization so that was one of the first things that became approved as a treatment for carbon 19 because it is generally safe there's a couple of different things people generally test for like blood typing you want to match the donor and recipient and then Rh factors but other than that it appears to be safe so if well what would happen if you didn't match wouldn't hurt you or would it just not help you suppose you had the wrong blood type match yeah it could it could definitely hurt you down the road I'm not you know it has been done without blood type matching in fact when it was first used or the reports I've seen when it was first users from the early 1900's and they were not doing blood type matching at that time but all those reports showed significant improvement well well if you had to guess based on you know isn't there there are two other cases where they've used this convalescent blood serum approach right was it HIV was one well I don't think it was used or I'm not aware of it being used for HIV but the treatment for HIV is monoclonal antibodies and same with Ebola and so it's similar in a way because convalescent serum therapy is used basically using antibodies it's more of a kind of gross product of antibodies where you're just taking everything under the Sun that's in somebody's serum and giving it to somebody else and you're not selecting for one specific antibody but it has been used in SARS there is actually a guy who got the 1901 Nobel Prize for the development of Serapis in he solved diphtheria epidemic in Germany in the 1890s by using serum therapies and that's kind of where it started and so he's the pioneer in the field his name's Emil von Behring oh do you do you know what it would take to scale this up like let's say that in a few weeks we said yes this is the thing we need more of this given that you have to actually take it from people unless you're using machines to clone it I guess how quickly can I know you did some calculations on how quickly you could scale up well what what would you guess I know this is an unfair question off the top of your head but let's say if we were to say start today and said all right we want to get everybody kind of lesson blood serum therapy like how close are we to being able to do that is that something that scales up very well um I think that is generally reserved for the people that are in poor condition you know in the hospital so not everybody is gonna need it but for those people it would be possible I is obviously gonna be dependent on your area New York got hit so hard that I don't know if they would have been able to keep up with demand but generally speaking you have about 5% of cases who end up in the ICU and those are the people that would be candidates to receive the therapy would they really because why wouldn't you give it to people even before they have it so that they if they did get it they could handle it more easily just because of scalability it is tough you need to do on plasmapheresis to get the plasma from donors you also have to be checking people ahead of time to make sure that they actually had an antibody response against the virus let me ask you some sort of detailed questions if you're gonna draw blood from one person and turn that one person's blood into antibodies how long with the whole process take from putting the needle in to draw the blood to to having it in your hand and ready to give somebody else I think that you can do quest my paresis in a couple of hours it depends on obviously how much you're trying to harvest the amount that the FDA allows I believe for a donation is a liter per week or two liters every two weeks and then in the study that you're taught you were talking about they used about 500 milliliters which is a half a liter per patient so it looks like I don't lift it you don't need go ahead it did to simplify that each donor giving one donation could handle how many people for it looks like if over a 2-week donation period or two Huffer one one donation if i donate blood once how many people would that handle to say oh that's good that's kind of hard to scale isn't it yes exactly and so that's why I say it should be reserved for only the people that are in poor condition or in the hospital now if you looked into the I don't understand the the differences or the nuances of monoclonal where you're just taking you know the best antibodies you can get from one real person and then you're cloning it with machines to scale it up it is is there a limit to how quickly you can do that if you just keep building machines you couldn't could we do a ventilator type thing or we just say all right everybody's building monoclonal devices if you looked into those do you know yeah so that they're not yeah those are the first therapies that will come online for carbon 19 is that monoclonal antibody therapies it takes a little bit of time to develop because of the process you build what are called hybridomas and that's a fusion between a cancer cell and an antibody creating cell and the cancer cell makes it immortal and then the antibody secreting cell is fused and it starts just producing antibodies and mass and then you can create a ton of those cells they're all identical and make a bunch of antibodies in a bioreactor and that's being done now it just takes a little bit of time to identify the specific antibody secreting cell you want to use that's making good antibodies now what once you've identified the antibodies isn't it just a question of making more of those machines and more of those facilities couldn't couldn't you just keep scaling it up and definitely correct yeah you could especially if you know you somebody identified a good antibody secreting cell and then made the hybridomas and if they were to share those with other people and kind of decentralize the production and make it scale faster that would maybe be a good way to do it there's also you know you should be probably combining a lot of different hybridomas to get good coverage for your antibodies make sure that they're there's a good protection there do you have you heard I haven't seen any news coverage of the monoclonal anything didn't do you know if anybody's getting any traction actually doing that I haven't seen anything that's become available yet with those I've seen some anecdotal reports about strong protection there I think last week there's a report from a company that said they had a good candidate but you know it's still a little early and the other thing is that there's a difference between having an antibody that you can see recognizes Kovan 19 and then also whether that antibody neutralizes the virus so I've actually seen some evidence in my hands where somebody can test positive for antibodies that recognize the virus but those antibodies don't necessarily neutralize the virus and then conversely somebody could have a low level of antibodies that you know recognize the virus but those antibodies are very strong at neutralizing so there is no off there so and do we have any more visibility on how long antibodies would last let's say you got them either naturally by having it recovering or you got it from from the plasma from somebody else do you know Israeli difference and how long they would last you know that that's a good question I don't you might expect there to be a shorter window for donor antibodies because they might have start to get marked as non-self by your immune system and then kind of removed but it's a tough thing to study because you know you start to get this mix of potentially like antibodies made by yourself and antibodies from the the donor and how do you differentiate which one came from which but I think generally like two years is what a lot of people say if you look at data from the original SARS patients two years of protection is what people are getting at least so I'm at least some got protection out to seventeen years so now would what do you say that it comes down to literally just how fast we can make this stuff I mean that's really the gating factor right because at this point we kind of know it's safe and we kind of know it works or all common sense says it works right I mean it would be hard to imagine it doesn't work yeah yeah it definitely works and one of the limitations is just getting access to the people who are producing those antibodies so that then you can kind of identify those antibody secreting cells and scale this so I would encourage anybody that's ever had it and recovered to look into getting tested for antibodies and look into donating their serum for a convalescence serum therapy because every you could donate every week or every couple weeks and that serum can be banked for the future where maybe in the fall we have a second wave or something so I think we should be stockpiling serum now I'm in anticipation for the fall and winter kinda interesting so there's there's I'd never heard before which is we have all these strategic stockpiles of everything from oil to PPE and ventilators it would make perfect sense stuff a national stack the stockpile temporarily I don't know how long you can store this stuff but it would that makes perfect sense of a national stockpile of convalescence Europe that's actually a great idea I hope somebody's watching this we can do something about that yeah yeah good yeah and that like I said requires people who have had it to get tested for the antibodies and be kind of active participants I think that a lot of people are looking for something that they can do to help nowadays and that's one pretty easy way to do it and you know I I think that those people should get paid to donate their serum a lot of them have probably accrued pretty significant hospital bills along the way and this would be a way to offset those bills for them and oh yeah oh now you now you're this is interesting so you're talking about how this might be a money-making thing are you aware of anybody who's ever charged for their antibodies for any kind of situation does that ever happen I'm not aware of a specific instance where somebody's donated their antibodies because they just had greatest antibodies out there but you know there's plasma donation centers all across the country I don't know the name of one offhand but I know there's national chains of plasma donation centers and they pay people the this is very interesting because you know I I think that the patriotic mood in the country at the moment is so high that you could get all the all the blood you wanted but basically if the if the President of the United States said here's the deal if you've tested positive I need you to do this go in and offer your blood we're gonna try to see how much where you get I believe that patriotism alone would give you all the blood you wanted but if you really wanted to take it to the next level people are people and if you could offer more money to let's say go in in time or the third or fourth time as you're suggesting I would imagine that a monetary incentive would probably have a gigantic yes yeah yeah and I I've talked to some people about you know the monetary incentive and people get a little bit uneasy sometimes about that but my perspective is that you know it's going to be administered in the hospital and is the hospital making money yeah so why shouldn't I don't yeah exactly now so we've got safety it's really just a production problem it seems to me and it's almost like gosh it feels like this is such a big deal you know every the the biggest deal of course is wearing masks but I would think that the second most promising thing you know if we have to wait for vaccines for months and months but the things that we can do now the second most promising thing is probably this what do you say yeah in terms of things that we know that work and not having to wait around for something that you know may never actually happen right we there's no guarantee that we'll have a vaccine or anything like that but we know this works and so you know why not embrace it well we also pursue other avenues to solve the problem so that is yeah good I was just going to point out so I started a company that we're going to be doing antibody testing as well and I'm specifically doing a neutralization tests which means we're not just testing for the presence of antibody we're testing to see whether your antibodies neutralize the virus and we plan to take that data and kind of publish it on publish the de-identified data on open source dashboards for anybody to check out just so everybody can get a general sense of where their community is in terms of relative protection and then I plan on creating an avenue for people who test positive for neutralizing antibodies to be sent information on how to donate their plasma right so we'll be identifying those candidates and so then they should be told you know here's what you can do if you're interested in helping other people with your unique situation or unique set of antibodies so I've been watching the comments and I just I just want to call out something that I always talked about winning attitudes and losing attitudes and I'm watching a lot of losing attitudes in the in the comments specific specifically people who don't quite appreciate and I'm gonna make them appreciate it now the power of your talent stack because people are sort of saying oh data analyst what's that got to do with this but the whole point is that you knew how to draw blood you know how to get these tests you've got what do you say your background was a biological what by bioscience yeah so he's in a bioscience background so it basically compiled a whole bunch of skills together including starting a new business initiative to try to help with the coronavirus so what do you see Ian jumping in and I was watching this from the beginning and on day one Ian was saying alright I have this at a talents how can I help in this coronavirus thing and then I've been watching as you've you've you've grabbed you know like one piece of one piece of it at a time and tried to assemble it into something that would be bigger than the parts and I've been I've been completely impressed not only at the early data visualization stuff you're doing because initially you were doing data visualization some of the best ones I've seen on the internet and then you found that your talent stack gave you all the way to here and actually you know there you know it could be a you know one of the pivotal at least informational parts of what would be the second most important thing we do after masks so I'm very impressed at why you've done and for those who are we don't have the winning mindset what the hell did you guys do let me just say that while you're out in the line to you limit to your tricks because because you know there's always going to be somebody on the air blah blah I hear this all you know hey you're a cartoonist why you do this little lot but all of those people you're not very successful I'll bet because if you're worried about staying in your lane and you're worried that people only have one Talent Ian's got more than one Talent sorry if you only have one Talent maybe you don't understand how that works but if you put enough talents together you have a superpower and I think this is a perfect example of it so Ian thank you for being a a patriot and I mean that seriously because in in times of crisis not everybody runs toward the fire and you did you know on day one you were running toward the emergency you know what can I do and we need more of you and less of the people who were picking I I really appreciate that Scott and I just want to point out before I go that I can't do it all by myself I have a lot of help from Mikkel Staten and Brianna Knight they've been helping me get cure hub going and you know it everything's you know about being on a team and winning team and you're we're all in this together and no one person can make anything work and I think it's you gotta treat life like a positive sum game and then you'll start to find some yes all over the place well that's something that's America in a in a nutshell right there so thank you so much do you want to name a URL that you want people look at yeah you can go to cure - hub calm and we have a system in place where you can sign up and get reserve your spot in line to get antibody test it and then you don't pay anything but you'll get on our mailing list and then as soon as we have the antibody tests approved which should be a couple weeks then we'll let you know and then you can join the study and you know donate a sample to get tested we'll test you and yeah that's all right so thank you thank you again thanks for being a great guest I'm gonna go on with the rest of my program and I'll catch up with you can I do one thing I miss the simultaneous sip can I get another one live I gotta do it all right I will give you the the first ever second simultaneous sip and all you need is a cup Ramona glass tank any kind you ready cheers Cheers the second simultaneous sip even better than first all right thanks again thank you bye all right so you know I as much as that the topic is interesting because in my opinion is probably the most important topic besides masks but I also wanted you to get get a feel for Ian you know just just to feel for what you are fellow citizens if you're American and I'm sure it's happening in every country around the world people are just jumping into the breach any people are running toward this thing like crazy you know when this is over when this is over you're gonna be really proud that you were a human because humans are pretty awesome and and and humans have done remarkable things in the past several months and there's a lot more to come so you know we're all lost in the details and just trying to get through life and you make it to the next time you can buy groceries and I know that that's got to be the focus but when this is done when this is done there gonna be some real real things to be proud about all right let's talk about some other things I got a suggestion on the locals platform where I've moved a lot of my non Dilbert stuff from Anholt I don't know that's one name and Nolt and alt anyway I don't know his real name but he started referring to people who watched CNN and MSNBC as the poorly educated how much do you love that so I'm gonna I gonna adopt that that concept so instead of what I'd be what I used to be saying was you know it's two movies on one screen and some people are siloed in their in their news and they don't see the news from the other side and I used to sort of describe it as you know in engineering terms but I thought this is so much more powerful just say it oh you only watch these networks well you're among the poorly educated because it's literally jus literally poorly educated which i think is hilarious cuz you know how much they can hate that so apparently in the in the polls including a Fox News poll Biden is ahead of Trump by way more than even Hillary was ahead of Trump at the same time so apparently Biden is doing great by staying at a public and just gaffing himself and decompressing at his basis now I don't know what could be more ridiculous or more funny than the fact that Joe Biden is his basement you literally just you know decomposing and he and he sees what great honestly are you ever just a home and he just are laughing about the whole Joe Biden in the basement situation because you know the the Biden and the basement things sort of crept up on us right like it was like hey I think there's this virus and move on all right yeah and yet in like it looks like it might be coming this way all right and maybe we should you know stay away from public a little bit and next thing you know a major candidate for president is living in his basement and babbling nonsense and be and because we sort of got there gradually we've sort of accepted it go on are you are you sure uh-huh can you tell me that you've never just you just sit there by yourself and suddenly you just sort of realise the situation we're in would Joe Biden decomposing in his basement and leading leading in the polls to be the next president of the United States I don't have his fingers on the nuclear on the nuclear button if that's not funny to you it is but here's the thing that's funniest I'm not positive so you know you can't you know don't hold me to this later I'm not positive but I think I just think we might be witnessing the greatest practical joke of all talk and what I mean by the greatest practical joke is I think I can't prove this I think conservatives are massively lying to pollsters because it's funny right dude tell me I'm wrong don't you don't you sort of suspect because if you were saying to yourself okay I get that president Trump's not popular and you know all the Democrats are gonna vote for whoever the Democrat is yeah I get that you know that's gonna explain most of what you see right but the the fact that Biden's down there decomposing and leading the polls strongly suggests it strongly suggests that what we're seeing is a really large national scale practical joke because if the if the polls still say Biden by eight points and then Trump wins by eight points it's going to be the greatest troll of all time honestly it will be it will be the most epic practical joke ever played in the history of practical jokes and I think that's what's happening am I wrong get am i completely off-base because I'm seeing a lot of people in the comments were saying I think you're right I think you're right I think the Republicans are just lying to the pollsters because it's funny speaking of funny pranks Alyssa Milano got photographed wearing a crochet mask and you can imagine how the internet reacted to her crochet mask they of course said hey there are holes in your crochet therefore you fool you idiot you dumb Democrat you bite in supporting fool you fool how could you wear a crochet map mask and worse yet if you're gonna wear a crochet mask don't get your photograph taken if you're famous and so of course Twitter went on fire it's like doesn't know anything you idiot your crochet bass and then Alyssa Milano waited wait hold hold hold and then it was ylim Alyssa Milano tweets to one of her critics carbon filter inside love it was a trap it was a trap do you think she knew that people were gonna get out or about her crochet mask which she says and you know I think it's probably true she says as a carbon filter on the inside it probably does probably does because if you've got those good n95 masks they're the ugliest of the masks so if she figured out a way to put a you know a more pleasant cover over the ugliest mask which is also the best kind of mask maybe maybe I don't know if it was an n95 but she said a carbon filter so maybe that's good - all right if you're not watching I've said this a million times but if you're not following Mike's or a on Twitter you're missing one of the best shows it's like it's like a TV show that just goes on all the time it doesn't have a beginning or an end like every time every time I get on Twitter I don't see like five certain if it's quotes and everyone does it makes you stop and go huh but this one if you want to understand how to operate on the next level this this tweet from sorry this made me laugh for two days if this is the whole tweet he goes self-confidence triggers mediocre man now of course the beauty of it is you can't complain about without being labeled the mediocre man so it's like this perfect little trap it's like I want to complain about that because I'm really mad about your self-confidence I'm like sort of but if I do complain about it does that make me a mediocre man so yeah watching sort of itch build these little Twitter traps for a mediocre man that's one of the funniest things I've seen on the Internet telehealth has taken off I said this before but there's even more signs of it have you seen all the commercials telehealth is basically just huge now we thought that might happen but apparently it is happening the the last thing benefit we're gonna get from telehealth it's gonna be gigantic and the ability to you know practice across state lines which i think will become permanent would be huge and again thank you to all of you who helped make that happen so that's just checking in on that because it's such a big topic and it's go in the right direction so it's always good to hear some good news all right what else we got going here there's some kind of drug called ivermectin that's getting some good reviews and I guess it it can interact with other medications and has some side effects and stuff but there were some initial trials that you know sort of look good so I've heard nekton there's another one I think that in the next over the next few weeks you just gonna hear one therapeutic after another and it's just gonna be all positive news now if you've done the math I did this last night in periscope I was talking about all the things which have cut the wrists down so masks are supposed to be 75 percent effective distance of course is completely effective maybe vitamin D maybe summer will make a difference in the warm weather you know maybe what we've learned about nursing homes and how to protect them maybe what we've learned about ventilator use not to kill people with ventilators if you if you take each each of these many pieces of good news each of them individually reduces risk by some percentage from 75% with masks down to maybe vitamin D makes a difference or maybe it's just correlation we don't know if it's causation yet but maybe hydroxychloroquine and zinc if you get a Merlin he's 20% benefit maybe there's some people we can get with this convalescent blood serum so we now have off the top of my head maybe 10 to 12 different things we've either developed as tool or learned which also allows us to reduce risk I feel like we have all the tools to within a few weeks we're gonna have the risk down to it's gonna approach to zero I mean it's almost gonna disappear I think monoclonal antibody is almost ready somebody says yeah and that could be huge the monoclonal antibodies just could be huge all right and then somebody says primer primarily immune system strength let me ask you this I want to see this in the comments when when this whole thing started I was advising everybody to just make sure they took care of their immune system so in other words you know get out get a little light exercise get some Sun get some sleepy right you know all the usual things how many of you have done that how many of you in the comments it'll take a little time like here but in the comments tell me if you feel that you've done something that would boost your immune system have you have you intentionally boosted your immune system with all the yeses Wow almost every person every so far every person who's answering you saying yes think about that well what kind of what kind of change does that make in your life and in civilization if suddenly 370 million people just decided to get serious about boosting their immunity and their health oh my god I am so impressed uh for those of you who are listening to this it is a non broken string of yeses I've never seen so much agreement somebody lost 20 pounds bicycle riding outdoors yes definitely yes yes yes yes immune system way up yes oh my goodness I am so so impressed very impressed I've never seen anything like this are you as impressed as I am take take a look at these comments coming by they're still absolutely solidly yes holy cow this is one of the this is the most underreported story of the year isn't it wouldn't you say this is the most underreported story if if we had not had a corona virus and suddenly you found that 370 million Americans and I'm guessing other countries doing something similar if you found that you know hundreds of millions of people suddenly took seriously their health what did we just do to the entire health care cost of this country how much of this is going to become habit you know I'm wondering if you think that you'll be able to turn this into habit the trouble is you know a lot of us not going to work in the normal ways we don't have the normal schedule so it's gonna be harder when you're trying to work it in with your normal schedule but wow I am so impressed with all of you genuinely somebody stopped smoking congratulations congratulations on stopping smoking that is hard alright so well that might be the good news for this may be our healthcare cost just took 20% hit simply because we're we're in better shape and we know how to do this so where can you outdoors shoot I don't understand that question all right well I'm impressed with you all and I'm gonna leave you on that note hope you learned something today and I'll talk to you tonight

um did you wonder where I was I'm two

minutes late

I couldn't get my Wi-Fi working a little

power outage last night s things up but

I'm good now or back and that means it's

time for a little thing you call

simultaneous it I call it that too

and all it takes is a cup of mud or a

glass of tanker gels to design a Kent

injector flies got vessel of any kind

hello with your favorite liquid I like

coffee

and join me now for the unparalleled

pleasure the dopamine the end of the day

the thing that makes everything better

including the damn pandemic it's called

the simultaneous if and it happens now

go mmm

now if you joined us last night I had a

little technical difficulty I was trying

to bring on a special guest to talk

about convalescent blood serum and as

soon as he's ready we're gonna try that

again this morning so I'll wait to wait

till see when Ian gets on all right

let's tell him we're good now in the

news my favorite story is that President

Trump apparently wanted to go golfing

this weekend

Behati didn't want it to be the biggest

story so what do you do if you want to

go golfing and you're the president and

you don't want it to be the biggest

story for three days well on the way out

the door to golf what you do is you to

send a tweet that accuses Joe

Scarborough of murder

they have to appreciate how much fun

that is now of course now for the family

of the victim who died many years ago

but the fact that Trump would accuse

somebody of murder before he goes

golfing is beautiful so I see Ian as

joined so let me just finish the story a

little Adam on now here's my take of

that now on one hand it's completely

outrageous and inappropriate that the

President of the United States would

accuse Joe Scarborough of murder when

there's no indication that he actually

murdered anybody there was some young

woman who hit her head and died in his

office years ago now that's all we know

and she had some health problem that

suggests that she just passed out yet

but the fact that the president would

say that now you say to yourself well

that's all wrong that is so wrong that

is wrong on a level that's deeper than

any wrongness except except we are

talking about Joe Scarborough who did

lie about the president in the worst

possible way for years I believe he

accused the president of suggesting

people should drink bleach that never

happened I think he suggested the

President had called neo-nazis in

Charlottesville fine people that never

happened

so is it fundamentally different to

accuse somebody of being pro-nazi versus

saying you murdered your girlfriend

they're not that different really

because once you have accepted that you

can say absolutely anything in the

political context there's just no

penalty you can say absolutely anything

the president just took the rules and

said what are the rules of the rules are

you can say anything really just

anything I can just make up anything and

I can just say it

public and it's a headline all right how

about joe scarborough's a murderer we'll

see how that goes

went pretty well all right let's see if

we get Jana Ian on the line this will be

a test of the technology I think we got

it

I think we got it Oh seriously because I

know we had a Wi-Fi problem yesterday

and it looks like we got a Wi-Fi problem

today well whatever the problem is

doesn't look like that's gonna get

solved I'll try it one more time but

then I think we should maybe give up on

this if it doesn't work this time

yeah and we'll try you one more time

yeah hey let's make this work the this

is the first time the technology has

worked more than five seconds so I feel

good about it

that's a good sign all right good strong

signal all right Ian first of all let me

see if I can pronounce your name

correctly

Ian Hill guard Martius pretty close yes

yes you nailed it all right can you tell

the audience what your background is and

how that relates specifically to the

convalescent blood plasma testing

situation give them a little background

on you okay so my background is that I

worked in bioscience for about ten years

and then I ended up kind of leaving

academic bioscience and taught myself to

program and become a data analyst and

started working in corporate and for a

corporation as a data analyst and when

the co good stuff started to hit I would

figure out ways to harvest public data

to do public data analysis that I could

publish so to help people understand the

situation a little better and then

through that process I started to you

know think about different answers that

I thought we needed

that maybe we weren't getting from the

media and one of the things I thought

about as well as you know what can we do

now what can we do before there's a

vaccine because there's going to be

people who can't wait that long

and the development of new therapeutics

that takes so long that a lot of people

would end up dying while they wait and

so you know we got to figure something

out

in the middle so tell us what you did

because I was I was sort of following

the law

early on and and you put together your

own tests right

well it wasn't necessarily my own test I

bought a commercially available test kit

I just happened to become aware of its

existence pretty early I suppose in the

way that I became aware of it is that I

just got like a spam email because you

know when you buy something from a

vendor they put you on a mailing list

and then they always blast out these

kind of spam advertisements and so I got

one of those that said oh hey we have

these Ovid 19 antibody tests and so I

thought oh I want to buy one of

those and my friend and I were just

going to test ourselves so we so I

bought one and then it had space for 40

tests and so I thought well I might as

well just fill this whole thing up and

run 40 tests and kind of get a better

sense of how many people are positive

because at the time it was unclear of

how far spread the virus had been so so

you are really I think you might have

been the first person who did and an

amateur or professional test of how many

people had antibodies do you know

anybody tested before you know I as far

as I know I was the first report or I

did publish the first report about or on

a community kind of serum survey for

over nineteen antibodies now so you've

been sort of

paying attention his little serum

antibody thing and I know there was a

there was a article in The Wall Street

Journal that said they had some small 39

people or something and how did that go

so yeah we positive on this

convalescence Europe I mean the idea of

taking blood from somebody who's been

infected and recovered and putting their

antibodies and somebody else what's the

state of that in terms of the science I

know you're surveying the field there

yeah so on Friday I believe the first

convalescent serum therapy clinical

study was published in the authors claim

it was the first in the world publish or

at least the largest and so they did

treat 39 patients like you said with

convalescence serum therapy and it was

controlled so there was a group that did

not receive that treatment and there was

a significant improvement in survival

with the group that did receive the

convalescent serum therapy there was

about twelve point eight percent death

rate for the convalescent serum therapy

group but it was twenty four point four

percent for those who didn't receive it

so that means that the serum therapy cut

the death rate in half and that was for

people who were pretty close to death to

begin with and I think I saw in the

article that they they just assumed it

would work better if he had it earlier

but hasn't been tested I guess now is

there any reason to think that any of

this would ever be dangerous does it it

doesn't go through it wouldn't have to

go I know this is sort of outside your

area but I don't think this would have

to go through whole FDA with it the

whole FDA approval because it's their

antibodies is something we know well

enough that we don't need to go through

the whole tastic well well it is

actually FDA approved now at least with

an emergency use authorization so that

was one of the first things that became

approved as a treatment for carbon 19

because it is generally safe there's a

couple of different things

people generally test for like blood

typing you want to match the donor and

recipient and then Rh factors but other

than that it appears to be safe

so if well what would happen if you

didn't match wouldn't hurt you or would

it just not help you

suppose you had the wrong blood type

match yeah it could it could definitely

hurt you down the road I'm not you know

it has been done without blood type

matching in fact when it was first used

or the reports I've seen when it was

first users from the early 1900's and

they were not doing blood type

matching at that time but all those

reports showed significant improvement

well well if you had to guess based on

you know isn't there there are two other

cases where they've used this

convalescent blood serum approach right

was it HIV was one well I don't think it

was used or I'm not aware of it being

used for HIV but the treatment for HIV

is monoclonal antibodies and same with

Ebola and so it's similar in a way

because convalescent serum therapy is

used basically using antibodies it's

more of a kind of gross product of

antibodies where you're just taking

everything under the Sun that's in

somebody's serum and giving it to

somebody else and you're not selecting

for one specific antibody but it has

been used in SARS there is actually a

guy who got the 1901 Nobel Prize for the

development of Serapis in he solved

diphtheria epidemic in Germany in the

1890s by using serum therapies and

that's kind of where it started and so

he's the pioneer in the field

his name's Emil von Behring oh do you do

you know

what it would take to scale this up like

let's say that in a few weeks we said

yes this is the thing we need more of

this given that you have to actually

take it from people unless you're using

machines to clone it I guess how quickly

can I know you did some calculations on

how quickly you could scale up well what

what would you guess I know this is an

unfair question off the top of your head

but let's say if we were to say start

today and said all right we want to get

everybody kind of lesson blood serum

therapy like how close are we to being

able to do that is that something that

scales up very well um I think that is

generally reserved for the people that

are in poor condition you know in the

hospital so not everybody is gonna need

it but for those people it would be

possible I is obviously gonna be

dependent on your area New York got hit

so hard that I don't know if they would

have been able to keep up with demand

but generally speaking you have about 5%

of cases who end up in the ICU and those

are the people that would be candidates

to receive the therapy would they really

because why wouldn't you give it to

people even before they have it so that

they if they did get it they could

handle it more easily just because of

scalability it is tough you need to do

on plasmapheresis to get the plasma from

donors you also have to be checking

people ahead of time to make sure that

they actually had an antibody response

against the virus let me ask you some

sort of detailed questions if you're

gonna draw blood from one person and

turn that one person's blood into

antibodies how long with the whole

process take from putting the needle in

to draw the blood to to having it in

your hand and ready to give somebody

else I think that you can do quest my

paresis in a couple of hours it depends

on obviously how much you're trying to

harvest the amount that the FDA allows I

believe for

a donation is a liter per week or two

liters every two weeks and then in the

study that you're taught you were

talking about they used about 500

milliliters which is a half a liter per

patient so it looks like I don't lift it

you don't need go ahead it did to

simplify that each donor giving one

donation could handle how many people

for it looks like if over a 2-week

donation period or two Huffer one one

donation if i donate blood once how many

people would that handle to say oh

that's good

that's kind of hard to scale isn't it

yes exactly and so that's why I say it

should be reserved for only the people

that are in poor condition or in the

hospital now if you looked into the I

don't understand the the differences or

the nuances of monoclonal where you're

just taking you know the best antibodies

you can get from one real person and

then you're cloning it with machines to

scale it up it is is there a limit to

how quickly you can do that if you just

keep building machines you couldn't

could we do a ventilator type thing or

we just say all right everybody's

building monoclonal devices if you

looked into those do you know yeah so

that they're not yeah those are the

first therapies that will come online

for carbon 19 is that monoclonal

antibody therapies it takes a little bit

of time to develop because of the

process you build what are called

hybridomas and that's a fusion between a

cancer cell and an antibody creating

cell and the cancer cell makes it

immortal and then the antibody secreting

cell is fused and it starts just

producing antibodies and mass and then

you can create a ton of those cells

they're all identical and make a bunch

of antibodies in a bioreactor

and that's being done now it just takes

a little bit of time to identify the

specific antibody secreting cell

you want to use that's making good

antibodies now what once you've

identified the antibodies isn't it just

a question of making more of those

machines and more of those facilities

couldn't couldn't you just keep scaling

it up and definitely correct yeah you

could especially if you know you

somebody identified a good antibody

secreting cell and then made the

hybridomas and if they were to share

those with other people and kind of

decentralize the production and make it

scale faster that would maybe be a good

way to do it there's also you know you

should be probably combining a lot of

different hybridomas to get good

coverage for your antibodies make sure

that they're there's a good protection

there do you have you heard I haven't

seen any news coverage of the monoclonal

anything didn't do you know if anybody's

getting any traction actually doing that

I haven't seen anything that's become

available yet with those I've seen some

anecdotal reports about strong

protection there I think last week

there's a report from a company that

said they had a good candidate but you

know it's still a little early and the

other thing is that there's a difference

between having an antibody that you can

see recognizes Kovan 19 and then also

whether that antibody neutralizes the

virus so I've actually seen some

evidence in my hands where somebody can

test positive for antibodies that

recognize the virus but those antibodies

don't necessarily neutralize the virus

and then conversely somebody could have

a low level of antibodies that you know

recognize the virus but those antibodies

are very strong at neutralizing so there

is no off there so and do we have any

more visibility on how long antibodies

would last let's say you got them either

naturally by having it recovering or you

got it from

from the plasma from somebody else do

you know Israeli difference and how long

they would last you know that that's a

good question I don't you might expect

there to be a shorter window for donor

antibodies because they might have start

to get marked as non-self by your immune

system and then kind of removed but it's

a tough thing to study because you know

you start to get this mix of potentially

like antibodies made by yourself and

antibodies from the the donor and how do

you differentiate which one came from

which but I think generally like two

years is what a lot of people say if you

look at data from the original SARS

patients two years of protection is what

people are getting at least so I'm at

least some got protection out to

seventeen years so now would what do you

say that it comes down to literally just

how fast we can make this stuff I mean

that's really the gating factor right

because at this point we kind of know

it's safe and we kind of know it works

or all common sense says it works right

I mean it would be hard to imagine it

doesn't work yeah yeah it definitely

works and one of the limitations is just

getting access to the people who are

producing those antibodies so that then

you can kind of identify those antibody

secreting cells and scale this so I

would encourage anybody that's ever had

it and recovered to look into getting

tested for antibodies and look into

donating their serum for a convalescence

serum therapy because every you could

donate every week or every couple weeks

and that serum can be banked for the

future where maybe in the fall we have a

second wave or something so I think we

should be stockpiling serum now I'm in

anticipation for the fall and winter

kinda interesting so there's there's

I'd never heard before which is we have

all these strategic stockpiles of

everything from oil to PPE and

ventilators it would make perfect sense

stuff a national stack the stockpile

temporarily I don't know how long you

can store this stuff but it would that

makes perfect sense of a national

stockpile of convalescence Europe that's

actually a great idea I hope somebody's

watching this we can do something about

that yeah yeah good yeah and that like I

said requires people who have had it to

get tested for the antibodies and be

kind of active participants I think that

a lot of people are looking for

something that they can do to help

nowadays and that's one pretty easy way

to do it and you know I I think that

those people should get paid to donate

their serum a lot of them have probably

accrued pretty significant hospital

bills along the way and this would be a

way to offset those bills for them and

oh yeah oh now you now you're this is

interesting so you're talking about how

this might be a money-making thing are

you aware of anybody who's ever charged

for their antibodies for any kind of

situation does that ever happen I'm not

aware of a specific instance where

somebody's donated their antibodies

because they just had greatest

antibodies out there but you know

there's plasma donation centers all

across the country I don't know the name

of one offhand but I know there's

national chains of plasma donation

centers and they pay people the this is

very interesting because you know I I

think that the patriotic mood in the

country at the moment is so high that

you could get all the all the blood you

wanted but basically if the if the

President of the United States said

here's the deal if you've tested

positive I need you to do this go in and

offer your blood we're gonna try to see

how much where you get I believe that

patriotism alone would give you all the

blood you wanted but if you really

wanted to take it to the next level

people are people and if you could offer

more money to let's say go in

in time or the third or fourth time as

you're suggesting I would imagine that a

monetary incentive would probably have a

gigantic yes yeah yeah and I I've talked

to some people about you know the

monetary incentive and people get a

little bit uneasy sometimes about that

but my perspective is that you know it's

going to be administered in the hospital

and is the hospital making money yeah so

why shouldn't I don't yeah exactly

now so we've got safety it's really just

a production problem it seems to me and

it's almost like gosh it feels like this

is such a big deal you know every the

the biggest deal of course is wearing

masks but I would think that the second

most promising thing you know if we have

to wait for vaccines for months and

months but the things that we can do now

the second most promising thing is

probably this what do you say yeah in

terms of things that we know that work

and not having to wait around for

something that you know may never

actually happen right we there's no

guarantee that we'll have a vaccine or

anything like that

but we know this works and so you know

why not embrace it well we also pursue

other avenues to solve the problem so

that is yeah good I was just going to

point out so I started a company that

we're going to be doing antibody testing

as well and I'm specifically doing a

neutralization tests which means we're

not just testing for the presence of

antibody we're testing to see whether

your antibodies neutralize the virus and

we plan to take that data and kind of

publish it on publish the de-identified

data on open source dashboards for

anybody to check out just so everybody

can get a general sense of where their

community is in terms of relative

protection and then I plan on creating

an avenue for people who test positive

for neutralizing antibodies to be sent

information

on how to donate their plasma right so

we'll be identifying those candidates

and so then they should be told you know

here's what you can do if you're

interested in helping other people with

your unique situation or unique set of

antibodies so I've been watching the

comments and I just I just want to call

out something that I always talked about

winning attitudes and losing attitudes

and I'm watching a lot of losing

attitudes in the in the comments

specific specifically people who don't

quite appreciate and I'm gonna make them

appreciate it now the power of your

talent stack because people are sort of

saying oh data analyst what's that got

to do with this but the whole point is

that you knew how to draw blood you know

how to get these tests you've got what

do you say your background was a

biological what by bioscience yeah so

he's in a bioscience background so it

basically compiled a whole bunch of

skills together including starting a new

business initiative to try to help with

the coronavirus so what do you see

Ian jumping in and I was watching this

from the beginning and on day one

Ian was saying alright I have this at a

talents how can I help in this

coronavirus thing and then I've been

watching as you've you've you've grabbed

you know like one piece of one piece of

it at a time and tried to assemble it

into something that would be bigger than

the parts and I've been I've been

completely impressed not only at the

early data visualization stuff you're

doing because initially you were doing

data visualization some of the best ones

I've seen on the internet and then you

found that your talent stack gave you

all the way to here and actually you

know there you know it could be a you

know one of the pivotal at least

informational parts of what would be the

second most important thing we do after

masks so I'm very impressed at why

you've done and for those who are we

don't have the winning mindset what the

hell did you guys do let me just say

that while you're out in the line to you

limit to your tricks because because you

know there's always going to be somebody

on the air blah blah I hear this all

you know hey you're a cartoonist why you

do this little lot but all of those

people you're not very successful I'll

bet because if you're worried about

staying in your lane and you're worried

that people only have one Talent Ian's

got more than one Talent sorry if you

only have one Talent maybe you don't

understand how that works but if you put

enough talents together you have a

superpower and I think this is a perfect

example of it so Ian thank you for being

a a patriot and I mean that seriously

because in in times of crisis not

everybody runs toward the fire and you

did you know on day one you were running

toward the emergency you know what can I

do and we need more of you and less of

the people who were picking I I really

appreciate that Scott and I just want to

point out before I go that I can't do it

all by myself

I have a lot of help from Mikkel Staten

and Brianna Knight

they've been helping me get cure hub

going and you know it everything's you

know about being on a team and winning

team and you're we're all in this

together and no one person can make

anything work and I think it's you gotta

treat life like a positive sum game and

then you'll start to find some yes all

over the place well that's something

that's America in a in a nutshell right

there so thank you so much do you want

to name a URL that you want people look

at yeah you can go to cure - hub calm

and we have a system in place where you

can sign up and get reserve your spot in

line to get antibody test it and then

you don't pay anything but you'll get on

our mailing list and then as soon as we

have the antibody tests approved which

should be a couple weeks then we'll let

you know and then you can join the study

and you know donate a sample to get

tested we'll test you and yeah that's

all right so thank you thank you again

thanks for being a great guest

I'm gonna go on with the rest of my

program and I'll catch up with you can I

do one thing I miss the simultaneous sip

can I get another one live I gotta do it

all right I will give you the the first

ever second simultaneous sip and all you

need is a cup Ramona glass tank any kind

you ready cheers Cheers

the second simultaneous sip even better

than first all right thanks again thank

you bye

all right so you know I as much as that

the topic is interesting because in my

opinion is probably the most important

topic besides masks but I also wanted

you to get get a feel for Ian you know

just just to feel for what you are

fellow citizens if you're American and

I'm sure it's happening in every country

around the world people are just jumping

into the breach any people are running

toward this thing like crazy you know

when this is over when this is over

you're gonna be really proud that you

were a human because humans are pretty

awesome and and and humans have done

remarkable things in the past several

months and there's a lot more to come so

you know we're all lost in the details

and just trying to get through life and

you make it to the next time you can buy

groceries and I know that that's got to

be the focus but when this is done when

this is done there gonna be some real

real things to be proud about all right

let's talk about some other things I got

a suggestion on the locals platform

where I've moved a lot of my non Dilbert

stuff from Anholt

I don't know that's one name and Nolt

and alt anyway I don't know his real

name but he started referring to people

who watched CNN and MSNBC as the poorly

educated

how much do you love that so I'm gonna I

gonna adopt that that concept so instead

of what I'd be what I used to be saying

was you know it's two movies on one

screen and some people are siloed in

their in their news and they don't see

the news from the other side and I used

to sort of describe it as you know in

engineering terms but I thought this is

so much more powerful just say it oh you

only watch these networks

well you're among the poorly educated

because it's literally jus literally

poorly educated which i think is

hilarious cuz you know how much they can

hate that so apparently in the in the

polls including a Fox News poll Biden is

ahead of Trump by way more than even

Hillary was ahead of Trump at the same

time so apparently Biden is doing great

by staying at a public and just gaffing

himself and decompressing at his basis

now I don't know what could be more

ridiculous or more funny than the fact

that Joe Biden is his basement you

literally just you know decomposing and

he and he sees what great honestly are

you ever just a home and he just are

laughing about the whole Joe Biden in

the basement situation because you know

the the Biden and the basement things

sort of crept up on us right like it was

like hey I think there's this virus and

move on all right

yeah and yet in like it looks like it

might be coming this way all right and

maybe we should you know stay away from

public a little bit and next thing you

know a major candidate for president is

living in his basement and babbling

nonsense and be and because we sort of

got there gradually we've sort of

accepted it

go on are you are you sure uh-huh

can you tell me that you've never just

you just sit there by yourself and

suddenly you just sort of realise the

situation we're in would Joe Biden

decomposing in his basement and leading

leading in the polls to be the next

president of the United States I don't

have his fingers on the nuclear on the

nuclear button if that's not funny to

you it is but here's the thing that's

funniest I'm not positive so you know

you can't you know don't hold me to this

later

I'm not positive but I think I just

think we might be witnessing the

greatest practical joke of all talk and

what I mean by the greatest practical

joke is I think I can't prove this

I think conservatives are massively

lying to pollsters because it's funny

right dude

tell me I'm wrong don't you don't you

sort of suspect because if you were

saying to yourself okay I get that

president Trump's not popular and you

know all the Democrats are gonna vote

for whoever the Democrat is yeah I get

that you know that's gonna explain most

of what you see right but the the fact

that Biden's down there decomposing and

leading the polls strongly suggests it

strongly suggests that what we're seeing

is a really large national scale

practical joke because if the if the

polls still say Biden by eight points

and then Trump wins by eight points it's

going to be the greatest troll of all

time honestly it will be it will be the

most epic practical joke ever played in

the history of practical jokes and I

think that's what's happening am I wrong

get am i completely off-base because I'm

seeing a lot of people in the comments

were saying I think you're right I think

you're right I think the Republicans are

just lying to the pollsters because it's

funny speaking of funny pranks Alyssa

Milano got photographed wearing a

crochet mask and you can imagine how the

internet reacted to her crochet mask

they of course said hey there are holes

in your crochet therefore you fool you

idiot you dumb Democrat you bite in

supporting fool you fool how could you

wear a crochet map mask and worse yet if

you're gonna wear a crochet mask don't

get your photograph taken if you're

famous

and so of course Twitter went on fire

it's like doesn't know anything you

idiot your crochet bass and then Alyssa

Milano waited wait hold hold hold and

then it was ylim Alyssa Milano tweets to

one of her critics carbon filter inside

love

it was a trap it was a trap do you think

she knew that people were gonna get out

or about her crochet mask which she says

and you know I think it's probably true

she says as a carbon filter on the

inside it probably does probably does

because if you've got those good n95

masks they're the ugliest of the masks

so if she figured out a way to put a you

know a more pleasant cover over the

ugliest mask which is also the best kind

of mask maybe maybe I don't know if it

was an n95 but she said a carbon filter

so maybe that's good - all right if

you're not watching I've said this a

million times but if you're not

following Mike's or a on Twitter

you're missing one of the best shows

it's like it's like a TV show that just

goes on all the time it doesn't have a

beginning or an end like every time

every time I get on Twitter I don't see

like five certain if it's quotes and

everyone does it makes you stop and go

huh but this one if you want to

understand how to operate on the next

level this this tweet from sorry

this made me laugh for two days if this

is the whole tweet he goes

self-confidence triggers mediocre man

now of course the beauty of it is you

can't complain about without being

labeled the mediocre man so it's like

this perfect little trap it's like I

want to complain about that because I'm

really mad about your self-confidence

I'm like sort of but if I do

complain about it

does that make me a mediocre man so yeah

watching sort of itch build these little

Twitter traps for a mediocre man that's

one of the funniest things I've seen on

the Internet

telehealth has taken off I said this

before but there's even more signs of it

have you seen all the commercials

telehealth is basically just huge now we

thought that might happen but apparently

it is happening the the last thing

benefit we're gonna get from telehealth

it's gonna be gigantic and the ability

to you know practice across state lines

which i think will become permanent

would be huge and again thank you to all

of you who helped make that happen so

that's just checking in on that because

it's such a big topic and it's go in the

right direction so it's always good to

hear some good news all right what else

we got going here there's some kind of

drug called ivermectin that's getting

some good reviews and I guess it it can

interact with other medications and has

some side effects and stuff but there

were some initial trials that you know

sort of look good so I've heard nekton

there's another one I think that in the

next over the next few weeks you just

gonna hear one therapeutic after another

and it's just gonna be all positive news

now if you've done the math I did this

last night in periscope I was talking

about all the things which have cut the

wrists down so masks are supposed to be

75 percent effective distance of course

is completely effective maybe vitamin D

maybe summer will make a difference in

the warm weather you know maybe what

we've learned about nursing homes and

how to protect them maybe what we've

learned about ventilator use not to kill

people with ventilators if you if you

take each each of these many pieces of

good news each of them individually

reduces risk by some percentage from 75%

with masks down to maybe vitamin D makes

a difference or maybe it's just

correlation we don't know if it's

causation yet but maybe

hydroxychloroquine and zinc if you get a

Merlin he's 20% benefit maybe there's

some people we can get with this

convalescent blood serum so we now have

off the top of my head maybe 10 to 12

different things we've either developed

as

tool or learned which also allows us to

reduce risk I feel like we have all the

tools to within a few weeks we're gonna

have the risk down to it's gonna

approach to zero I mean it's almost

gonna disappear I think monoclonal

antibody is almost ready somebody says

yeah and that could be huge the

monoclonal antibodies just could be huge

all right and then somebody says primer

primarily immune system strength let me

ask you this I want to see this in the

comments when when this whole thing

started I was advising everybody to just

make sure they took care of their immune

system so in other words you know get

out get a little light exercise get some

Sun get some sleepy right you know all

the usual things how many of you have

done that how many of you in the

comments it'll take a little time like

here but in the comments tell me if you

feel that you've done something that

would boost your immune system have you

have you intentionally boosted your

immune system with all the yeses Wow

almost every person every so far every

person who's answering you saying yes

think about that well what kind of what

kind of change does that make in your

life and in civilization if suddenly 370

million people just decided to get

serious about boosting their immunity

and their health oh my god I am so

impressed uh for those of you who are

listening to this it is a non broken

string of yeses I've never seen so much

agreement somebody lost 20 pounds

bicycle riding outdoors yes definitely

yes yes yes yes immune system way up yes

oh my goodness I am so so impressed very

impressed I've never seen anything like

this are you as impressed as I am take

take a look at these

comments coming by they're still

absolutely solidly yes holy cow this is

one of the this is the most

underreported story of the year isn't it

wouldn't you say this is the most

underreported story if if we had not had

a corona virus and suddenly you found

that 370 million Americans and I'm

guessing other countries doing something

similar if you found that you know

hundreds of millions of people suddenly

took seriously their health what did we

just do to the entire health care cost

of this country how much of this is

going to become habit you know I'm

wondering if you think that you'll be

able to turn this into habit the trouble

is you know a lot of us not going to

work in the normal ways we don't have

the normal schedule so it's gonna be

harder when you're trying to work it in

with your normal schedule but wow I am

so impressed with all of you genuinely

somebody stopped smoking congratulations

congratulations on stopping smoking that

is hard alright so well that might be

the good news for this may be our

healthcare cost just took 20% hit simply

because we're we're in better shape and

we know how to do this so where can you

outdoors shoot I don't understand that

question

all right well I'm impressed with you

all and I'm gonna leave you on that note

hope you learned something today and

I'll talk to you tonight